STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
wsb1WD repeat and SOCS box-containing protein 1; Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. (423 aa)    
Predicted Functional Partners:
ash2l
Ash2-like, histone lysine methyltransferase complex subunit.
   
 
 0.797
cul5a
Cullin 5a; Belongs to the cullin family.
    
 0.762
kansl2
KAT8 regulatory NSL complex subunit 2.
   
 
 0.752
spsb1
SplA/ryanodine receptor domain and SOCS box-containing 1.
   
 
 0.731
rbbp5
Retinoblastoma-binding protein 5.
   
 
0.719
spsb4a
SplA/ryanodine receptor domain and SOCS box-containing 4a.
   
 
 0.715
hipk2
Homeodomain-interacting protein kinase 2.
    
 
 0.686
rbx1
Ring-box 1, E3 ubiquitin protein ligase.
   
 0.672
elocb
Elongin C paralog b; Belongs to the SKP1 family.
   
 0.649
eloca
Elongin C paralog a; Belongs to the SKP1 family.
   
 0.648
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.