STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mtmr2Myotubularin-related protein 2; Phosphatase that acts on lipids with a phosphoinositol headgroup. Has phosphatase activity towards phosphatidylinositol 3- phosphate and phosphatidylinositol 3,5-bisphosphate (By similarity). (620 aa)    
Predicted Functional Partners:
mtmr12
Myotubularin-related protein 12; Acts as an adapter for the myotubularin phosphatase mtm1 to regulate mtm1 protein stability and possibly its intracellular location. By stabilizing mtm1 protein levels, required for skeletal muscle maintenance but not for myogenesis. In skeletal muscle cells, does not regulate mtm1 subcellular localization.
   
0.940
pikfyve
Phosphatidylinositol phosphate 5-kinase type III isoform d.
   
 
 0.936
pik3c2b
Phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta; Belongs to the PI3/PI4-kinase family.
    
 0.919
cdipt
CDP-diacylglycerol--inositol 3-phosphatidyltransferase.
     
 0.914
FIG4
FIG4 phosphoinositide 5-phosphatase.
      
 0.846
pik3c3
Phosphatidylinositol 3-kinase catalytic subunit type 3.
     
 0.832
sh3tc2
SH3 domain and tetratricopeptide repeats 2.
      
 0.812
pik3c2a
Phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family.
   
 0.757
pik3c2g
Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma; Belongs to the PI3/PI4-kinase family.
    
 0.749
inpp4ab
Inositol polyphosphate-4-phosphatase type I Ab.
   
 
 0.739
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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