STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fam91a1Protein FAM91A1; As component of the WDR11 complex may act together with TBC1D23 to facilitate the golgin-mediated capture of vesicles generated using AP-1. (831 aa)    
Predicted Functional Partners:
C3H17orf75
Zgc:153240.
   
 
 0.880
tbc1d23
TBC1 domain family member 23; Putative Rab GTPase-activating protein which plays a role in vesicular trafficking. Involved in endosome-to-Golgi trafficking. Acts as a bridging protein by binding simultaneously to golgins, located at the trans-Golgi, and to the WASH complex, located on endosome-derived vesicles (By similarity). Plays a role in brain development. May act as a general inhibitor of innate immunity signaling (By similarity).
   
  
 0.825
bet1
Novel protein similar to vertebrate BET1 homolog (S. cerevisiae) (BET1).
      
 0.755
cpda
Carboxypeptidase D, a.
   
  
 0.755
gosr1
Golgi SNAP receptor complex member 1; Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor.
   
  
 0.755
dscc1
Sister chromatid cohesion protein DCC1; Loads pcna onto primed templates regulating velocity, spacing and restart activity of replication forks. May couple DNA replication to sister chromatid cohesion (By similarity).
      
 0.748
akap1b
A kinase (PRKA) anchor protein 1b.
      
 0.745
gosr2
Golgi SNAP receptor complex member 2; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network.
      
 0.735
atad2
ATPase family AAA domain-containing 2.
      
 0.731
scfd1
Sec1 family domain-containing 1; Belongs to the STXBP/unc-18/SEC1 family.
   
  
 0.723
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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