STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
phox2aPaired-like homeobox 2A. (280 aa)    
Predicted Functional Partners:
dbh
Dopamine beta-hydroxylase (dopamine beta-monooxygenase).
   
  
 0.635
glrbb
Glycine receptor beta subunit 2; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
   
  
 0.596
stm
Protein starmaker; Essential for the formation of otoliths in the inner ear of developing larvae and for the perception of gravity and acceleration. May be one of the organic components of the ortholiths.
      
 0.570
barx2
BARX homeobox 2.
      
0.559
hand2
Heart- and neural crest derivatives-expressed protein 2; Essential for myocardial and pectoral fin differentiation, patterning and morphogenesis.
   
 
 0.517
th
Tyrosine hydroxylase.
   
  
 0.499
Alx3
Uncharacterized protein.
      
 0.484
crot
Carnitine O-octanoyltransferase; Belongs to the carnitine/choline acetyltransferase family.
      
 0.479
INSM2
INSM transcriptional repressor 2.
   
  
 0.474
kif21a
Kinesin family member 21A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
      
 0.474
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.