STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gcgrbGlucagon receptor b; Belongs to the G-protein coupled receptor 2 family. (509 aa)    
Predicted Functional Partners:
gcgb
Glucagon b.
    
 0.989
gcgra
Glucagon receptor a; Belongs to the G-protein coupled receptor 2 family.
  
  
0.904
gnas
GNAS complex locus.
    
 0.879
ins
Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
      
 0.767
gcga
Glucagon a.
    
 
 0.755
insb
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
      
 0.745
gnb2
Guanine nucleotide-binding protein (G protein), beta polypeptide 2.
    
 0.734
gnb1b
Guanine nucleotide binding protein (G protein), beta polypeptide 1, like.
    
 0.734
gnb4b
Guanine nucleotide-binding protein (G protein), beta polypeptide 4b.
    
 0.734
gnb3a
Novel protein similar to guanine nucleotide binding protein (G protein) beta polypeptide family.
    
 0.676
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.