STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
camkvbCaM kinase-like vesicle-associated protein; Does not appear to have detectable kinase activity. (436 aa)    
Predicted Functional Partners:
TMEM8B
Si:dkey-84j12.1.
      
 0.858
loxl4
Lysyl oxidase-like 4.
   
 
 0.677
grik4
Glutamate receptor, ionotropic, kainate 4.
   
  
 0.674
ilf3b
Interleukin enhancer-binding factor 3 homolog; RNA-binding protein that plays an essential role in the biogenesis of circular RNAs (circRNAs) which are produced by back- splicing circularization of pre-mRNAs. Within the nucleus, promotes circRNAs processing by stabilizing the regulatory elements residing in the flanking introns of the circularized exons. Plays thereby a role in the back-splicing of a subset of circRNAs. As a consequence, participates in a wide range of transcriptional and post- transcriptional processes. Binds to poly-U elements and AU-rich elements (AREs) in the 3'-UT [...]
      
 0.661
dmrta2
Doublesex- and mab-3-related transcription factor A2; May be involved in sexual development; Belongs to the DMRT family.
      
 0.649
tshz2
Teashirt zinc finger homeobox 2.
      
 0.624
cacna1g
Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...]
      
 0.564
calm2a
Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases.
   
 
 0.554
slc9a1b
Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
      
 0.452
fezf2
Fez family zinc finger protein 2; Transcription repressor. Component of the regulatory cascade that controls the development of dopaminergic (DA) and serotonergic (5HT) neurons.
   
 
 0.449
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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