STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ttc36Tetratricopeptide repeat protein 36; Belongs to the TTC36 family. (187 aa)    
Predicted Functional Partners:
hpda
4-hydroxyphenylpyruvate dioxygenase; Key enzyme in the degradation of tyrosine; Belongs to the 4HPPD family.
   
 
 0.748
fah
Fumarylacetoacetase.
   
  
 0.726
hpdb
4-hydroxyphenylpyruvate dioxygenase.
   
 
 0.699
hgd
Homogentisate 1,2-dioxygenase.
   
  
 0.698
uox
Uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.
   
  
 0.689
dpep1
Dipeptidase; Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.
   
  
 0.682
fgg
Fibrinogen, gamma polypeptide.
   
  
 0.634
cldn15lb
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
   
    0.615
fga
Fibrinogen alpha chain.
   
  
 0.598
fgb
Fibrinogen, B beta polypeptide.
   
  
 0.569
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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