STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hoga14-hydroxy-2-oxoglutarate aldolase, mitochondrial; Catalyzes the final step in the metabolic pathway of hydroxyproline. (324 aa)    
Predicted Functional Partners:
grhpra
Novel protein similar to human glyoxylate reductase/hydroxypyruvate reductase (GRHPR); Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 0.996
grhprb
Glyoxylate reductase/hydroxypyruvate reductase b; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 0.988
agxtb
Serine--pyruvate aminotransferase.
   
 
 0.978
got2b
Aspartate aminotransferase.
   
 0.937
hao2
Hydroxyacid oxidase 2 (long chain).
   
 
 0.937
got2a
Aspartate aminotransferase.
   
 0.936
got1
Aspartate aminotransferase.
   
 0.930
hao1
Hydroxyacid oxidase (glycolate oxidase) 1.
   
 
 0.923
agxta
Serine--pyruvate aminotransferase.
   
 
 0.921
dao.2
D-amino-acid oxidase, tandem duplicate 2.
   
 
 0.910
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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