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rfng protein (Danio rerio) - STRING interaction network
"rfng" - Beta-1,3-N-acetylglucosaminyltransferase radical fringe in Danio rerio
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second shell of interactors
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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rfngBeta-1,3-N-acetylglucosaminyltransferase radical fringe; Glycosyltransferase that initiates the elongation of O- linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules (By similarity). Regulates neurogenesis in the hindbrain; involved in boundary cell specification via Notch-mediated activation of wnt1 expression (362 aa)    
Predicted Functional Partners:
notch1a
Neurogenic locus notch homolog protein 1; Functions as a receptor for membrane-bound ligands jagged1, jagged2 and delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Involved in the maturation of both CD4+ [...] (1655 aa)
     
  0.852
notch2
Notch homolog 2 (2475 aa)
       
  0.842
notch3
Notch homolog 3 (2468 aa)
     
  0.841
notch1b
Notch homolog 1b (2465 aa)
     
  0.829
lfng
Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe; Glycosyltransferase that initiates the elongation of O- linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Involved in the correct formation of boundaries in the somites and hindbrain (By similarity). Required for Delta-Notch-mediated induction of hypochord cells at the lateral borders of the midline precursor domain (374 aa)
     
 
0.811
mfng
Beta-1,3-N-acetylglucosaminyltransferase manic fringe; Glycosyltransferase that initiates the elongation of O- linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules (360 aa)
         
0.811
pofut1
Protein O-fucosyltransferase 1 (395 aa)
     
   
  0.752
jag1a
Protein jagged-1a; Ligand for multiple Notch receptors and involved in the mediation of Notch signaling (By similarity). Seems to be involved in cell-fate decisions (1253 aa)
       
 
  0.725
v2rh32
Vomeronasal 2 receptor, h32 (855 aa)
           
  0.706
lhx2b
LIM homeobox 2b (427 aa)
       
 
  0.689
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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