node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
St6galnac2 | fkbp5 | ENSDARP00000132134 | ENSDARP00000038578 | Uncharacterized protein; Belongs to the glycosyltransferase 29 family. | Peptidylprolyl isomerase. | 0.742 |
adsl | fkbp5 | ENSDARP00000022310 | ENSDARP00000038578 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Peptidylprolyl isomerase. | 0.793 |
fkbp5 | St6galnac2 | ENSDARP00000038578 | ENSDARP00000132134 | Peptidylprolyl isomerase. | Uncharacterized protein; Belongs to the glycosyltransferase 29 family. | 0.742 |
fkbp5 | adsl | ENSDARP00000038578 | ENSDARP00000022310 | Peptidylprolyl isomerase. | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.793 |
fkbp5 | hsp90aa1.1 | ENSDARP00000038578 | ENSDARP00000022302 | Peptidylprolyl isomerase. | Heat shock protein HSP 90-alpha 1; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a [...] | 0.850 |
fkbp5 | hsp90aa1.2 | ENSDARP00000038578 | ENSDARP00000026065 | Peptidylprolyl isomerase. | Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2. | 0.835 |
fkbp5 | hsp90ab1 | ENSDARP00000038578 | ENSDARP00000014978 | Peptidylprolyl isomerase. | Heat shock protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interact [...] | 0.836 |
fkbp5 | nr3c1 | ENSDARP00000038578 | ENSDARP00000054263 | Peptidylprolyl isomerase. | Nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor). | 0.856 |
fkbp5 | pgr | ENSDARP00000038578 | ENSDARP00000109370 | Peptidylprolyl isomerase. | Progesterone receptor. | 0.759 |
fkbp5 | ptges3a | ENSDARP00000038578 | ENSDARP00000054236 | Peptidylprolyl isomerase. | Prostaglandin E synthase 3a (cytosolic). | 0.940 |
fkbp5 | stip1 | ENSDARP00000038578 | ENSDARP00000100503 | Peptidylprolyl isomerase. | Stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing protein). | 0.836 |
fkbp5 | tsc22d3 | ENSDARP00000038578 | ENSDARP00000054114 | Peptidylprolyl isomerase. | TSC22 domain family, member 3. | 0.806 |
hsp90aa1.1 | fkbp5 | ENSDARP00000022302 | ENSDARP00000038578 | Heat shock protein HSP 90-alpha 1; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a [...] | Peptidylprolyl isomerase. | 0.850 |
hsp90aa1.1 | hsp90aa1.2 | ENSDARP00000022302 | ENSDARP00000026065 | Heat shock protein HSP 90-alpha 1; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a [...] | Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2. | 0.905 |
hsp90aa1.1 | hsp90ab1 | ENSDARP00000022302 | ENSDARP00000014978 | Heat shock protein HSP 90-alpha 1; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a [...] | Heat shock protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interact [...] | 0.902 |
hsp90aa1.1 | nr3c1 | ENSDARP00000022302 | ENSDARP00000054263 | Heat shock protein HSP 90-alpha 1; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a [...] | Nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor). | 0.893 |
hsp90aa1.1 | pgr | ENSDARP00000022302 | ENSDARP00000109370 | Heat shock protein HSP 90-alpha 1; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a [...] | Progesterone receptor. | 0.707 |
hsp90aa1.1 | ptges3a | ENSDARP00000022302 | ENSDARP00000054236 | Heat shock protein HSP 90-alpha 1; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a [...] | Prostaglandin E synthase 3a (cytosolic). | 0.917 |
hsp90aa1.1 | stip1 | ENSDARP00000022302 | ENSDARP00000100503 | Heat shock protein HSP 90-alpha 1; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a [...] | Stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing protein). | 0.962 |
hsp90aa1.2 | fkbp5 | ENSDARP00000026065 | ENSDARP00000038578 | Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2. | Peptidylprolyl isomerase. | 0.835 |