node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
chd3 | chd4b | ENSDARP00000127601 | ENSDARP00000152065 | Chromodomain helicase DNA-binding protein 3. | Chromodomain helicase DNA-binding protein 4b. | 0.814 |
chd3 | gatad2ab | ENSDARP00000127601 | ENSDARP00000031168 | Chromodomain helicase DNA-binding protein 3. | GATA zinc finger domain-containing 2Ab. | 0.923 |
chd3 | gatad2b | ENSDARP00000127601 | ENSDARP00000036714 | Chromodomain helicase DNA-binding protein 3. | GATA zinc finger domain-containing 2B. | 0.960 |
chd3 | hdac1 | ENSDARP00000127601 | ENSDARP00000051798 | Chromodomain helicase DNA-binding protein 3. | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | 0.987 |
chd3 | kdm1a | ENSDARP00000127601 | ENSDARP00000080193 | Chromodomain helicase DNA-binding protein 3. | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | 0.880 |
chd3 | mta1 | ENSDARP00000127601 | ENSDARP00000152737 | Chromodomain helicase DNA-binding protein 3. | Metastasis-associated 1. | 0.913 |
chd3 | mta2 | ENSDARP00000127601 | ENSDARP00000119097 | Chromodomain helicase DNA-binding protein 3. | Metastasis-associated 1 family, member 2. | 0.877 |
chd3 | mta3 | ENSDARP00000127601 | ENSDARP00000107969 | Chromodomain helicase DNA-binding protein 3. | Metastasis-associated 1 family, member 3. | 0.819 |
chd3 | rbb4l | ENSDARP00000127601 | ENSDARP00000117542 | Chromodomain helicase DNA-binding protein 3. | Histone-binding protein RBBP7; Core histone-binding subunit that may target chromatin remodeling factors, histone acetyltransferases and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. | 0.968 |
chd3 | rbbp4 | ENSDARP00000127601 | ENSDARP00000048143 | Chromodomain helicase DNA-binding protein 3. | Histone-binding protein RBBP4; Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. | 0.933 |
chd4b | chd3 | ENSDARP00000152065 | ENSDARP00000127601 | Chromodomain helicase DNA-binding protein 4b. | Chromodomain helicase DNA-binding protein 3. | 0.814 |
chd4b | gatad2ab | ENSDARP00000152065 | ENSDARP00000031168 | Chromodomain helicase DNA-binding protein 4b. | GATA zinc finger domain-containing 2Ab. | 0.908 |
chd4b | gatad2b | ENSDARP00000152065 | ENSDARP00000036714 | Chromodomain helicase DNA-binding protein 4b. | GATA zinc finger domain-containing 2B. | 0.890 |
chd4b | hdac1 | ENSDARP00000152065 | ENSDARP00000051798 | Chromodomain helicase DNA-binding protein 4b. | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | 0.825 |
chd4b | kdm1a | ENSDARP00000152065 | ENSDARP00000080193 | Chromodomain helicase DNA-binding protein 4b. | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | 0.716 |
chd4b | mta1 | ENSDARP00000152065 | ENSDARP00000152737 | Chromodomain helicase DNA-binding protein 4b. | Metastasis-associated 1. | 0.828 |
chd4b | mta2 | ENSDARP00000152065 | ENSDARP00000119097 | Chromodomain helicase DNA-binding protein 4b. | Metastasis-associated 1 family, member 2. | 0.835 |
chd4b | mta3 | ENSDARP00000152065 | ENSDARP00000107969 | Chromodomain helicase DNA-binding protein 4b. | Metastasis-associated 1 family, member 3. | 0.840 |
chd4b | rbb4l | ENSDARP00000152065 | ENSDARP00000117542 | Chromodomain helicase DNA-binding protein 4b. | Histone-binding protein RBBP7; Core histone-binding subunit that may target chromatin remodeling factors, histone acetyltransferases and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. | 0.866 |
chd4b | rbbp4 | ENSDARP00000152065 | ENSDARP00000048143 | Chromodomain helicase DNA-binding protein 4b. | Histone-binding protein RBBP4; Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. | 0.878 |