STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
maddMAP-kinase-activating death domain. (1680 aa)    
Predicted Functional Partners:
mapkapk3
MAPK-activated protein kinase 3; Belongs to the protein kinase superfamily.
      
 0.743
trib2
Tribbles pseudokinase 2.
   
  
 0.690
rab27b
RAB27B, member RAS oncogene family.
     
 0.639
rab27a
RAB27A, member RAS oncogene family.
     
 0.639
dennd1a
DENN/MADD domain-containing 1A.
   
 
0.624
tnfrsf1a
Tumor necrosis factor receptor superfamily, member 1a.
    
 0.603
rab3gap2
RAB3 GTPase-activating protein subunit 2 (non-catalytic).
      
 0.596
rab3gap1
Rab3 GTPase-activating protein catalytic subunit; Probable catalytic subunit of a GTPase activating protein that has specificity for Rab3 subfamily. Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Specifically converts active Rab3-GTP to the inactive form Rab3-GDP (By similarity).
   
  
 0.594
fnbp4
Formin-binding protein 4.
   
  
 0.577
pibf1
Progesterone immunomodulatory-binding factor 1.
      
 0.574
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.