STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fstl5Follistatin-like 5. (854 aa)    
Predicted Functional Partners:
fstl3
Follistatin-like 3 (secreted glycoprotein).
   
  
 0.848
wfikkn2b
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain-containing 2b.
      
 0.778
tmeff1a
Transmembrane protein with EGF-like and two follistatin-like domains 1a.
      
 0.669
fstb
Follistatin 2.
      
 0.668
chrdl2
Chordin-like protein.
    
 
 0.656
fsta
Follistatin-A; Binds directly to activin and functions as an activin antagonist. Specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone (fsh) (By similarity). Inhibits bmp-signaling during later stages of development including late phases of dorsoventral patterning, to refine the early pattern set up by the interaction of chordino and bmp2/4. Not involved in organizer function or early phases of dorsoventral pattern formation.
      
 0.649
wfdc2
WAP four-disulfide core domain 2.
    
 
 0.585
ppef1
Serine/threonine-protein phosphatase with EF-hands.
      
 0.569
ca16b
Carbonic anhydrase XVI b.
   
 
 0.560
ptprga
Protein tyrosine phosphatase receptor type g a.
   
 
 0.557
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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