STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rap2abRAP2A, member of RAS oncogene family b. (183 aa)    
Predicted Functional Partners:
ccdc124
Coiled-coil domain-containing protein 124; Required for proper progression of late cytokinetic stages.
      
 0.863
rasgef1ba
Ras-GEF domain-containing family member 1B-A; Guanine nucleotide exchange factor (GEF) for Ras family proteins (in vitro).
      
 0.805
LOC110440055
Leucyl-tRNA synthetase a.
      
 0.742
RALGDS
Si:ch211-251j10.3.
    
 
 0.597
itsn2a
Intersectin 2a.
    
 
 0.581
itsn2b
Intersectin 2b.
    
 
 0.581
itsn1
Intersectin 1 (SH3 domain protein).
    
 
 0.551
ttc19
Tetratricopeptide repeat protein 19, mitochondrial; Required for the preservation of the structural and functional integrity of mitochondrial respiratory complex III by allowing the physiological turnover of the Rieske protein UQCRFS1. Involved in the clearance of UQCRFS1 N-terminal fragments, which are produced upon incorporation into the complex III and whose presence is detrimental for its catalytic activity.
    
 
 0.513
E9QJ85_DANRE
Si:ch211-274f20.2.
   
 
 0.499
im:7152348
Im:7152348.
    
 
 0.497
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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