STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
renRenin; Belongs to the peptidase A1 family. (395 aa)    
Predicted Functional Partners:
ace2
Angiotensin-converting enzyme.
     
 0.991
atp6ap2
ATPase H+-transporting accessory protein 2.
   
 0.989
ace
Angiotensin-converting enzyme.
     
 0.986
agt
Angiotensinogen; Belongs to the serpin family.
    
 0.973
mmel1
Membrane metallo-endopeptidase-like 1.
    
 0.834
ctsc
Cathepsin C; Belongs to the peptidase C1 family.
   
 0.793
ctsbb
Cathepsin Bb; Belongs to the peptidase C1 family.
   
 0.777
ctsba
Cathepsin B, a; Belongs to the peptidase C1 family.
   
 0.775
ctso
Cathepsin O; Belongs to the peptidase C1 family.
   
 0.760
ctsf
Cathepsin F; Belongs to the peptidase C1 family.
   
 0.758
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.