STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
spred1Sprouty-related EVH1 domain-containing 1. (391 aa)    
Predicted Functional Partners:
pik3r2
Phosphoinositide-3-kinase, regulatory subunit 2 (beta).
      
 0.958
nf1a
Neurofibromin 1a.
   
 0.935
egfl7
EGF-like-domain, multiple 7.
    
 
 0.857
nras
GTPase NRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family.
   
 0.836
spred2a
Sprouty-related EVH1 domain-containing 2a.
  
  
 
0.805
kras
V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog.
   
 0.761
fgfrl1a
Fibroblast growth factor receptor-like 1a.
     
 0.732
RASA2
RAS p21 protein activator 2.
     
 0.674
nf1b
Neurofibromin 1b.
    
 
 0.673
vcam1b
Vascular cell adhesion molecule 1b.
      
 0.670
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.