STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
paip1Poly(A)-binding protein-interacting protein 1. (419 aa)    
Predicted Functional Partners:
pabpc1l
Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.
   
 0.974
pabpc1a
Polyadenylate-binding protein 1A; Binds the poly(A) tail of mRNA (By similarity). Prevents mRNA deadenylation and confers poly(A) stability (By similarity). Stimulates the translation of mRNAs to which it is bound, acting, at least in part, with dazl (By similarity). Involved in the maternal-to-zygotic transition in early embryo via interaction with ybx1: interaction recruits pabpc1a on C5-methylcytosine (m5C)-containing maternal mRNAs, preventing their degradation. Belongs to the polyadenylate-binding protein type-1 family.
   
 0.972
pabpc1b
Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.
   
 0.963
eif4a1b
Eukaryotic translation initiation factor 4A, isoform 1B; Belongs to the DEAD box helicase family.
   
 0.958
pabpc4
Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.
   
 0.958
eif4a1a
Eukaryotic translation initiation factor 4A, isoform 1A.
   
 0.957
eif4a2
Eukaryotic translation initiation factor 4A, isoform 2; Belongs to the DEAD box helicase family.
   
 0.957
eif4ba
Eukaryotic translation initiation factor 4Ba.
   
 0.947
eif4eb
Eukaryotic translation initiation factor 4eb; Belongs to the eukaryotic initiation factor 4E family.
   
 0.910
eif4e1b
Eukaryotic translation initiation factor 4E-1B; Does not appear to be a mRNA-cap-binding protein.
   
 
 0.841
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (30%) [HD]