node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LOC100001991 | MMP23B | ENSDARP00000132990 | ENSDARP00000063241 | ADAM metallopeptidase with thrombospondin type 1 motif, 15b. | Matrix metallopeptidase 23B. | 0.750 |
LOC100001991 | loxl2a | ENSDARP00000132990 | ENSDARP00000064612 | ADAM metallopeptidase with thrombospondin type 1 motif, 15b. | Lysyl oxidase homolog 2A; Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine) (By similarity). Acts as a transcription corepressor and specifically mediates deamination of trimethylated 'Lys-4' of histone H3 (H3K4me3), a specific tag for epigenetic transcriptional activation (By similarity). Shows no activity against histone H3 when it is trimethylated on 'Lys-9' (H3K9me3) or 'Lys-27' (H3K27me3) or when 'Lys-4' is monomethylated (H3K4me1) or dimethylated (H3K4me2) (By similarity). Also medi [...] | 0.746 |
LOC100001991 | nrg2b | ENSDARP00000132990 | ENSDARP00000108874 | ADAM metallopeptidase with thrombospondin type 1 motif, 15b. | Neuregulin 2b. | 0.744 |
LOC100002059 | MMP23B | ENSDARP00000128297 | ENSDARP00000063241 | ADAM metallopeptidase with thrombospondin type 1 motif, 15b. | Matrix metallopeptidase 23B. | 0.752 |
LOC100002059 | loxl2a | ENSDARP00000128297 | ENSDARP00000064612 | ADAM metallopeptidase with thrombospondin type 1 motif, 15b. | Lysyl oxidase homolog 2A; Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine) (By similarity). Acts as a transcription corepressor and specifically mediates deamination of trimethylated 'Lys-4' of histone H3 (H3K4me3), a specific tag for epigenetic transcriptional activation (By similarity). Shows no activity against histone H3 when it is trimethylated on 'Lys-9' (H3K9me3) or 'Lys-27' (H3K27me3) or when 'Lys-4' is monomethylated (H3K4me1) or dimethylated (H3K4me2) (By similarity). Also medi [...] | 0.749 |
LOC100002059 | nrg2b | ENSDARP00000128297 | ENSDARP00000108874 | ADAM metallopeptidase with thrombospondin type 1 motif, 15b. | Neuregulin 2b. | 0.744 |
MMP23B | LOC100001991 | ENSDARP00000063241 | ENSDARP00000132990 | Matrix metallopeptidase 23B. | ADAM metallopeptidase with thrombospondin type 1 motif, 15b. | 0.750 |
MMP23B | LOC100002059 | ENSDARP00000063241 | ENSDARP00000128297 | Matrix metallopeptidase 23B. | ADAM metallopeptidase with thrombospondin type 1 motif, 15b. | 0.752 |
MMP23B | loxl2a | ENSDARP00000063241 | ENSDARP00000064612 | Matrix metallopeptidase 23B. | Lysyl oxidase homolog 2A; Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine) (By similarity). Acts as a transcription corepressor and specifically mediates deamination of trimethylated 'Lys-4' of histone H3 (H3K4me3), a specific tag for epigenetic transcriptional activation (By similarity). Shows no activity against histone H3 when it is trimethylated on 'Lys-9' (H3K9me3) or 'Lys-27' (H3K27me3) or when 'Lys-4' is monomethylated (H3K4me1) or dimethylated (H3K4me2) (By similarity). Also medi [...] | 0.556 |
MMP23B | nrg2b | ENSDARP00000063241 | ENSDARP00000108874 | Matrix metallopeptidase 23B. | Neuregulin 2b. | 0.483 |
aacs | loxl2a | ENSDARP00000002180 | ENSDARP00000064612 | Acetoacetyl-CoA synthetase; Activates acetoacetate to acetoacetyl-CoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Lysyl oxidase homolog 2A; Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine) (By similarity). Acts as a transcription corepressor and specifically mediates deamination of trimethylated 'Lys-4' of histone H3 (H3K4me3), a specific tag for epigenetic transcriptional activation (By similarity). Shows no activity against histone H3 when it is trimethylated on 'Lys-9' (H3K9me3) or 'Lys-27' (H3K27me3) or when 'Lys-4' is monomethylated (H3K4me1) or dimethylated (H3K4me2) (By similarity). Also medi [...] | 0.592 |
aacs | pcdh18a | ENSDARP00000002180 | ENSDARP00000108171 | Acetoacetyl-CoA synthetase; Activates acetoacetate to acetoacetyl-CoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Protocadherin 18a. | 0.519 |
loxl2a | LOC100001991 | ENSDARP00000064612 | ENSDARP00000132990 | Lysyl oxidase homolog 2A; Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine) (By similarity). Acts as a transcription corepressor and specifically mediates deamination of trimethylated 'Lys-4' of histone H3 (H3K4me3), a specific tag for epigenetic transcriptional activation (By similarity). Shows no activity against histone H3 when it is trimethylated on 'Lys-9' (H3K9me3) or 'Lys-27' (H3K27me3) or when 'Lys-4' is monomethylated (H3K4me1) or dimethylated (H3K4me2) (By similarity). Also medi [...] | ADAM metallopeptidase with thrombospondin type 1 motif, 15b. | 0.746 |
loxl2a | LOC100002059 | ENSDARP00000064612 | ENSDARP00000128297 | Lysyl oxidase homolog 2A; Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine) (By similarity). Acts as a transcription corepressor and specifically mediates deamination of trimethylated 'Lys-4' of histone H3 (H3K4me3), a specific tag for epigenetic transcriptional activation (By similarity). Shows no activity against histone H3 when it is trimethylated on 'Lys-9' (H3K9me3) or 'Lys-27' (H3K27me3) or when 'Lys-4' is monomethylated (H3K4me1) or dimethylated (H3K4me2) (By similarity). Also medi [...] | ADAM metallopeptidase with thrombospondin type 1 motif, 15b. | 0.749 |
loxl2a | MMP23B | ENSDARP00000064612 | ENSDARP00000063241 | Lysyl oxidase homolog 2A; Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine) (By similarity). Acts as a transcription corepressor and specifically mediates deamination of trimethylated 'Lys-4' of histone H3 (H3K4me3), a specific tag for epigenetic transcriptional activation (By similarity). Shows no activity against histone H3 when it is trimethylated on 'Lys-9' (H3K9me3) or 'Lys-27' (H3K27me3) or when 'Lys-4' is monomethylated (H3K4me1) or dimethylated (H3K4me2) (By similarity). Also medi [...] | Matrix metallopeptidase 23B. | 0.556 |
loxl2a | aacs | ENSDARP00000064612 | ENSDARP00000002180 | Lysyl oxidase homolog 2A; Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine) (By similarity). Acts as a transcription corepressor and specifically mediates deamination of trimethylated 'Lys-4' of histone H3 (H3K4me3), a specific tag for epigenetic transcriptional activation (By similarity). Shows no activity against histone H3 when it is trimethylated on 'Lys-9' (H3K9me3) or 'Lys-27' (H3K27me3) or when 'Lys-4' is monomethylated (H3K4me1) or dimethylated (H3K4me2) (By similarity). Also medi [...] | Acetoacetyl-CoA synthetase; Activates acetoacetate to acetoacetyl-CoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.592 |
loxl2a | mxf | ENSDARP00000064612 | ENSDARP00000128551 | Lysyl oxidase homolog 2A; Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine) (By similarity). Acts as a transcription corepressor and specifically mediates deamination of trimethylated 'Lys-4' of histone H3 (H3K4me3), a specific tag for epigenetic transcriptional activation (By similarity). Shows no activity against histone H3 when it is trimethylated on 'Lys-9' (H3K9me3) or 'Lys-27' (H3K27me3) or when 'Lys-4' is monomethylated (H3K4me1) or dimethylated (H3K4me2) (By similarity). Also medi [...] | Myxovirus (influenza virus) resistance F; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. | 0.587 |
loxl2a | nrg2b | ENSDARP00000064612 | ENSDARP00000108874 | Lysyl oxidase homolog 2A; Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine) (By similarity). Acts as a transcription corepressor and specifically mediates deamination of trimethylated 'Lys-4' of histone H3 (H3K4me3), a specific tag for epigenetic transcriptional activation (By similarity). Shows no activity against histone H3 when it is trimethylated on 'Lys-9' (H3K9me3) or 'Lys-27' (H3K27me3) or when 'Lys-4' is monomethylated (H3K4me1) or dimethylated (H3K4me2) (By similarity). Also medi [...] | Neuregulin 2b. | 0.573 |
loxl2a | pcdh18a | ENSDARP00000064612 | ENSDARP00000108171 | Lysyl oxidase homolog 2A; Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine) (By similarity). Acts as a transcription corepressor and specifically mediates deamination of trimethylated 'Lys-4' of histone H3 (H3K4me3), a specific tag for epigenetic transcriptional activation (By similarity). Shows no activity against histone H3 when it is trimethylated on 'Lys-9' (H3K9me3) or 'Lys-27' (H3K27me3) or when 'Lys-4' is monomethylated (H3K4me1) or dimethylated (H3K4me2) (By similarity). Also medi [...] | Protocadherin 18a. | 0.582 |
loxl2a | rab41 | ENSDARP00000064612 | ENSDARP00000069541 | Lysyl oxidase homolog 2A; Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine) (By similarity). Acts as a transcription corepressor and specifically mediates deamination of trimethylated 'Lys-4' of histone H3 (H3K4me3), a specific tag for epigenetic transcriptional activation (By similarity). Shows no activity against histone H3 when it is trimethylated on 'Lys-9' (H3K9me3) or 'Lys-27' (H3K27me3) or when 'Lys-4' is monomethylated (H3K4me1) or dimethylated (H3K4me2) (By similarity). Also medi [...] | RAB41, member RAS oncogene family. | 0.564 |