STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
loxl2aLysyl oxidase homolog 2A; Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine) (By similarity). Acts as a transcription corepressor and specifically mediates deamination of trimethylated 'Lys-4' of histone H3 (H3K4me3), a specific tag for epigenetic transcriptional activation (By similarity). Shows no activity against histone H3 when it is trimethylated on 'Lys-9' (H3K9me3) or 'Lys-27' (H3K27me3) or when 'Lys-4' is monomethylated (H3K4me1) or dimethylated (H3K4me2) (By similarity). Also medi [...] (737 aa)    
Predicted Functional Partners:
rnf115
Ring finger protein 115.
    
 
 0.809
zgc:56064
Serine/threonine-protein phosphatase.
   
 
 0.772
LOC100002059
ADAM metallopeptidase with thrombospondin type 1 motif, 15b.
    
 
 0.749
LOC100001991
ADAM metallopeptidase with thrombospondin type 1 motif, 15b.
    
 
 0.746
aacs
Acetoacetyl-CoA synthetase; Activates acetoacetate to acetoacetyl-CoA; Belongs to the ATP-dependent AMP-binding enzyme family.
    
 
 0.592
mxf
Myxovirus (influenza virus) resistance F; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
    
 
 0.587
pcdh18a
Protocadherin 18a.
    
 
 0.582
nrg2b
Neuregulin 2b.
    
 
 0.573
rab41
RAB41, member RAS oncogene family.
    
 
 0.564
MMP23B
Matrix metallopeptidase 23B.
    
 
 0.556
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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