STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aqp8a.1Aquaporin 8a, tandem duplicate 1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (260 aa)    
Predicted Functional Partners:
aqp11
Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
     
 0.978
aqp7
Aquaporin 7; Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
  
 0.962
aqp12
Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
   
 
 0.935
aqp10b
Aquaporin 10b; Belongs to the MIP/aquaporin (TC 1.A.8) family.
     
 0.903
Aqp9a
Uncharacterized protein.
      
 0.846
rhbdf1a
Inactive rhomboid protein 1; Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own. Belongs to the peptidase S54 family.
    
 
 0.823
lcmt1
Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family.
 
    
 0.821
rhbdf1b
Rhomboid 5 homolog 1b (Drosophila).
   
 
 0.767
aqp3a
Aqp3 protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
 
0.764
aqp9b
Aquaporin 9b; Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
  
0.753
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.