node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
abhd2b | cd74a | ENSDARP00000067326 | ENSDARP00000002547 | Monoacylglycerol lipase ABHD2; Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane. Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1- arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA). Also displays an ester hydrolase activity against acetyl ester, butanoate ester and hexadecanoate ester. Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2A [...] | CD74 molecule, major histocompatibility complex, class II invariant chain a. | 0.479 |
abhd2b | entpd2b | ENSDARP00000067326 | ENSDARP00000122424 | Monoacylglycerol lipase ABHD2; Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane. Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1- arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA). Also displays an ester hydrolase activity against acetyl ester, butanoate ester and hexadecanoate ester. Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2A [...] | Ectonucleoside triphosphate diphosphohydrolase 2b; Belongs to the GDA1/CD39 NTPase family. | 0.441 |
abhd2b | lyrm5b | ENSDARP00000067326 | ENSDARP00000113978 | Monoacylglycerol lipase ABHD2; Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane. Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1- arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA). Also displays an ester hydrolase activity against acetyl ester, butanoate ester and hexadecanoate ester. Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2A [...] | LYR motif-containing protein 5B; Belongs to the complex I LYR family. | 0.744 |
abhd2b | mgll | ENSDARP00000067326 | ENSDARP00000053462 | Monoacylglycerol lipase ABHD2; Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane. Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1- arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA). Also displays an ester hydrolase activity against acetyl ester, butanoate ester and hexadecanoate ester. Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2A [...] | Monoglyceride lipase. | 0.489 |
abhd2b | mid1ip1b | ENSDARP00000067326 | ENSDARP00000021980 | Monoacylglycerol lipase ABHD2; Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane. Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1- arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA). Also displays an ester hydrolase activity against acetyl ester, butanoate ester and hexadecanoate ester. Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2A [...] | Mid1-interacting protein 1-B; Involved in stabilization of microtubules. May play a role in the regulation of lipogenesis (By similarity); Belongs to the SPOT14 family. | 0.743 |
abhd2b | mthfd1l | ENSDARP00000067326 | ENSDARP00000061913 | Monoacylglycerol lipase ABHD2; Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane. Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1- arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA). Also displays an ester hydrolase activity against acetyl ester, butanoate ester and hexadecanoate ester. Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2A [...] | Methylenetetrahydrofolate dehydrogenase (NADP+-dependent) 1-like. | 0.540 |
abhd2b | nt5c2l1 | ENSDARP00000067326 | ENSDARP00000020283 | Monoacylglycerol lipase ABHD2; Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane. Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1- arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA). Also displays an ester hydrolase activity against acetyl ester, butanoate ester and hexadecanoate ester. Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2A [...] | 5'-nucleotidase, cytosolic II,-like 1. | 0.479 |
abhd2b | siae | ENSDARP00000067326 | ENSDARP00000059310 | Monoacylglycerol lipase ABHD2; Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane. Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1- arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA). Also displays an ester hydrolase activity against acetyl ester, butanoate ester and hexadecanoate ester. Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2A [...] | Sialic acid acetylesterase. | 0.832 |
abhd2b | tbx2a | ENSDARP00000067326 | ENSDARP00000027905 | Monoacylglycerol lipase ABHD2; Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane. Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1- arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA). Also displays an ester hydrolase activity against acetyl ester, butanoate ester and hexadecanoate ester. Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2A [...] | T-box transcription factor 2a. | 0.450 |
abhd2b | tubb6 | ENSDARP00000067326 | ENSDARP00000140249 | Monoacylglycerol lipase ABHD2; Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane. Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1- arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA). Also displays an ester hydrolase activity against acetyl ester, butanoate ester and hexadecanoate ester. Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2A [...] | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. | 0.452 |
cd74a | abhd2b | ENSDARP00000002547 | ENSDARP00000067326 | CD74 molecule, major histocompatibility complex, class II invariant chain a. | Monoacylglycerol lipase ABHD2; Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane. Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1- arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA). Also displays an ester hydrolase activity against acetyl ester, butanoate ester and hexadecanoate ester. Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2A [...] | 0.479 |
cd74a | lyrm5b | ENSDARP00000002547 | ENSDARP00000113978 | CD74 molecule, major histocompatibility complex, class II invariant chain a. | LYR motif-containing protein 5B; Belongs to the complex I LYR family. | 0.481 |
cd74a | mid1ip1b | ENSDARP00000002547 | ENSDARP00000021980 | CD74 molecule, major histocompatibility complex, class II invariant chain a. | Mid1-interacting protein 1-B; Involved in stabilization of microtubules. May play a role in the regulation of lipogenesis (By similarity); Belongs to the SPOT14 family. | 0.533 |
entpd2b | abhd2b | ENSDARP00000122424 | ENSDARP00000067326 | Ectonucleoside triphosphate diphosphohydrolase 2b; Belongs to the GDA1/CD39 NTPase family. | Monoacylglycerol lipase ABHD2; Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane. Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1- arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA). Also displays an ester hydrolase activity against acetyl ester, butanoate ester and hexadecanoate ester. Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2A [...] | 0.441 |
entpd2b | lyrm5b | ENSDARP00000122424 | ENSDARP00000113978 | Ectonucleoside triphosphate diphosphohydrolase 2b; Belongs to the GDA1/CD39 NTPase family. | LYR motif-containing protein 5B; Belongs to the complex I LYR family. | 0.455 |
entpd2b | mid1ip1b | ENSDARP00000122424 | ENSDARP00000021980 | Ectonucleoside triphosphate diphosphohydrolase 2b; Belongs to the GDA1/CD39 NTPase family. | Mid1-interacting protein 1-B; Involved in stabilization of microtubules. May play a role in the regulation of lipogenesis (By similarity); Belongs to the SPOT14 family. | 0.405 |
lyrm5b | abhd2b | ENSDARP00000113978 | ENSDARP00000067326 | LYR motif-containing protein 5B; Belongs to the complex I LYR family. | Monoacylglycerol lipase ABHD2; Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane. Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1- arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA). Also displays an ester hydrolase activity against acetyl ester, butanoate ester and hexadecanoate ester. Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2A [...] | 0.744 |
lyrm5b | cd74a | ENSDARP00000113978 | ENSDARP00000002547 | LYR motif-containing protein 5B; Belongs to the complex I LYR family. | CD74 molecule, major histocompatibility complex, class II invariant chain a. | 0.481 |
lyrm5b | entpd2b | ENSDARP00000113978 | ENSDARP00000122424 | LYR motif-containing protein 5B; Belongs to the complex I LYR family. | Ectonucleoside triphosphate diphosphohydrolase 2b; Belongs to the GDA1/CD39 NTPase family. | 0.455 |
lyrm5b | mid1ip1b | ENSDARP00000113978 | ENSDARP00000021980 | LYR motif-containing protein 5B; Belongs to the complex I LYR family. | Mid1-interacting protein 1-B; Involved in stabilization of microtubules. May play a role in the regulation of lipogenesis (By similarity); Belongs to the SPOT14 family. | 0.743 |