STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
abhd2bMonoacylglycerol lipase ABHD2; Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane. Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1- arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA). Also displays an ester hydrolase activity against acetyl ester, butanoate ester and hexadecanoate ester. Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2A [...] (422 aa)    
Predicted Functional Partners:
siae
Sialic acid acetylesterase.
      
 0.832
lyrm5b
LYR motif-containing protein 5B; Belongs to the complex I LYR family.
      
 0.744
mid1ip1b
Mid1-interacting protein 1-B; Involved in stabilization of microtubules. May play a role in the regulation of lipogenesis (By similarity); Belongs to the SPOT14 family.
   
  
 0.743
mthfd1l
Methylenetetrahydrofolate dehydrogenase (NADP+-dependent) 1-like.
      
 0.540
mgll
Monoglyceride lipase.
   
 0.489
cd74a
CD74 molecule, major histocompatibility complex, class II invariant chain a.
      
 0.479
nt5c2l1
5'-nucleotidase, cytosolic II,-like 1.
      
 0.479
tubb6
Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
      
 0.452
tbx2a
T-box transcription factor 2a.
      
 0.450
entpd2b
Ectonucleoside triphosphate diphosphohydrolase 2b; Belongs to the GDA1/CD39 NTPase family.
      
 0.441
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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