STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hyal6Hyaluronidase. (486 aa)    
Predicted Functional Partners:
gusb
Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family.
     
 0.910
idua
Alpha-L-iduronidase.
    
  0.902
ARSB
Arylsulfatase B.
   
 
  0.900
grn2
Granulin 2.
   
  
 0.744
rgs12b
Regulator of G protein-signaling 12b.
      
 0.742
has3
Hyaluronan synthase 3.
   
  
 0.674
has1
Hyaluronan synthase 1.
      
 0.673
cd74a
CD74 molecule, major histocompatibility complex, class II invariant chain a.
   
 
 0.614
itsn2a
Intersectin 2a.
   
 
 0.583
itsn2b
Intersectin 2b.
    
 
 0.581
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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