STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aff2AF4/FMR2 family, member 2. (1269 aa)    
Predicted Functional Partners:
tenm1
Teneurin transmembrane protein 1.
   
  
 0.859
znf296
Zinc finger protein 296.
    
 
 0.688
ANOS1
Uncharacterized protein.
      
 0.676
tnrc18
Trinucleotide repeat-containing 18.
    
 
 0.674
sema4ab
Semaphorin-4A isoform X1; Belongs to the semaphorin family.
      
 0.669
commd5
COMM domain-containing 5.
      
 0.669
cntnap5l
Contactin-associated protein family member 5-like.
      
 0.661
pcyt1ba
Phosphate cytidylyltransferase 1, choline, beta a.
   
  
 0.652
gpd2
Glycerol-3-phosphate dehydrogenase 2 (mitochondrial).
      
 0.649
chd8
Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/tp53-mediated apoptosis by recruiting histone H1 and preventing p53/tp53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (ctnnb1) activity. Negatively regulates ctnnb1-targeted gene expression by being recruited specifically to the promoter regions of several ctnnb1 responsive [...]
    
 
 0.611
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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