STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
spred2aSprouty-related EVH1 domain-containing 2a. (421 aa)    
Predicted Functional Partners:
spred1
Sprouty-related EVH1 domain-containing 1.
  
  
 
0.805
nf1a
Neurofibromin 1a.
    
 0.761
fgfrl1a
Fibroblast growth factor receptor-like 1a.
     
  0.700
raf1a-2
Raf-1 proto-oncogene, serine/threonine kinase a.
    
 
 0.690
hrasb
-Ha-ras Harvey rat sarcoma viral oncogene homolog, like.
   
 0.638
nras
GTPase NRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family.
   
 0.638
kras
V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog.
   
 0.638
nf1b
Neurofibromin 1b.
    
 
 0.618
UBB
Si:ch211-202a12.4.
     
  0.499
rps27a
Ribosomal protein S27a.
     
  0.499
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.