STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fam172aCotranscriptional regulator FAM172A homolog; May play role in the regulation of alternative splicing. May have hydrolase activity; Belongs to the FAM172 family. (415 aa)    
Predicted Functional Partners:
cpped1
Serine/threonine-protein phosphatase CPPED1; Protein phosphatase involved in the dephosphorylation of AKT kinase family.
      
 0.865
slf1
SMC5-SMC6 complex localization factor 1.
      
 0.852
puf60b
Poly(U)-binding-splicing factor PUF60-B; DNA- and RNA-binding protein, involved in transcription repression and pre-mRNA splicing.
   
  
 0.714
dcun1d3
DCN1-like protein.
      
 0.680
cwc27
Spliceosome-associated protein CWC27 homolog; As part of the spliceosome, plays a role in pre-mRNA splicing. Probable inactive PPIase with no peptidyl-prolyl cis-trans isomerase activity.
      
 0.647
mvb12a
Multivesicular body subunit 12A; Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (By similarity).
   
  
 0.608
rbm10
RNA-binding motif protein 10.
      
 0.601
hddc2
HD domain-containing protein 2; Belongs to the HDDC2 family.
      
 0.589
exoc4
Exocyst complex component 4.
      
 0.561
eftud2
Elongation factor Tu GTP-binding domain-containing 2.
      
 0.559
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.