node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
atoh7 | lhx2b | ENSDARP00000092102 | ENSDARP00000123264 | Protein atonal homolog 7; Transcription factor involved in the differentiation of retinal ganglion cells. | LIM homeobox 2b. | 0.517 |
atoh7 | otx2b | ENSDARP00000092102 | ENSDARP00000111153 | Protein atonal homolog 7; Transcription factor involved in the differentiation of retinal ganglion cells. | Homeobox protein OTX2; May play a role in very early embryogenesis, gastrulation, and the development and subdivision of the diencephalon and the midbrain. | 0.691 |
atoh7 | pax6a | ENSDARP00000092102 | ENSDARP00000135767 | Protein atonal homolog 7; Transcription factor involved in the differentiation of retinal ganglion cells. | Paired box protein Pax-6; Transcription factor expressed in spatially restricted regions of the neural tube during embryonic development; Belongs to the paired homeobox family. | 0.824 |
atoh7 | shha | ENSDARP00000092102 | ENSDARP00000125090 | Protein atonal homolog 7; Transcription factor involved in the differentiation of retinal ganglion cells. | Sonic hedgehog protein A N-product; Sonic hedgehog protein: The C-terminal part of the sonic hedgehog protein precursor displays an autoproteolysis and a cholesterol transferase activity (By similarity). Both activities result in the cleavage of the full-length protein into two parts (ShhN and ShhC) followed by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated ShhN (By similarity). Both activities occur in the reticulum endoplasmic (By similarity). Once cleaved, ShhC is degraded in the endoplasmic reticulum (By similarity). | 0.689 |
atoh7 | six3b | ENSDARP00000092102 | ENSDARP00000071625 | Protein atonal homolog 7; Transcription factor involved in the differentiation of retinal ganglion cells. | Sine oculis homeobox homolog 3b. | 0.812 |
atoh7 | sox2 | ENSDARP00000092102 | ENSDARP00000095266 | Protein atonal homolog 7; Transcription factor involved in the differentiation of retinal ganglion cells. | Transcription factor Sox-2; Transcriptional activator. May function as a switch in neuronal development (By similarity). Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). | 0.554 |
atoh7 | vsx2 | ENSDARP00000092102 | ENSDARP00000038309 | Protein atonal homolog 7; Transcription factor involved in the differentiation of retinal ganglion cells. | Visual system homeobox 2; Acts as a transcriptional regulator (By similarity). Mediates the differentiation of V2a interneurons (By similarity). Plays a role in eye development and organization of the neuroretina. | 0.905 |
lhx2b | atoh7 | ENSDARP00000123264 | ENSDARP00000092102 | LIM homeobox 2b. | Protein atonal homolog 7; Transcription factor involved in the differentiation of retinal ganglion cells. | 0.517 |
lhx2b | otx2b | ENSDARP00000123264 | ENSDARP00000111153 | LIM homeobox 2b. | Homeobox protein OTX2; May play a role in very early embryogenesis, gastrulation, and the development and subdivision of the diencephalon and the midbrain. | 0.453 |
lhx2b | pax6a | ENSDARP00000123264 | ENSDARP00000135767 | LIM homeobox 2b. | Paired box protein Pax-6; Transcription factor expressed in spatially restricted regions of the neural tube during embryonic development; Belongs to the paired homeobox family. | 0.485 |
lhx2b | shha | ENSDARP00000123264 | ENSDARP00000125090 | LIM homeobox 2b. | Sonic hedgehog protein A N-product; Sonic hedgehog protein: The C-terminal part of the sonic hedgehog protein precursor displays an autoproteolysis and a cholesterol transferase activity (By similarity). Both activities result in the cleavage of the full-length protein into two parts (ShhN and ShhC) followed by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated ShhN (By similarity). Both activities occur in the reticulum endoplasmic (By similarity). Once cleaved, ShhC is degraded in the endoplasmic reticulum (By similarity). | 0.695 |
lhx2b | six3b | ENSDARP00000123264 | ENSDARP00000071625 | LIM homeobox 2b. | Sine oculis homeobox homolog 3b. | 0.873 |
lhx2b | sox2 | ENSDARP00000123264 | ENSDARP00000095266 | LIM homeobox 2b. | Transcription factor Sox-2; Transcriptional activator. May function as a switch in neuronal development (By similarity). Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). | 0.669 |
lhx2b | vsx2 | ENSDARP00000123264 | ENSDARP00000038309 | LIM homeobox 2b. | Visual system homeobox 2; Acts as a transcriptional regulator (By similarity). Mediates the differentiation of V2a interneurons (By similarity). Plays a role in eye development and organization of the neuroretina. | 0.581 |
lhx2b | zic2a | ENSDARP00000123264 | ENSDARP00000026131 | LIM homeobox 2b. | ZIC family member 2 (Odd-paired homolog, Drosophila), A. | 0.423 |
lhx2b | zic2b | ENSDARP00000123264 | ENSDARP00000054065 | LIM homeobox 2b. | ZIC family member 2 (Odd-paired homolog, Drosophila) B. | 0.416 |
otx2b | atoh7 | ENSDARP00000111153 | ENSDARP00000092102 | Homeobox protein OTX2; May play a role in very early embryogenesis, gastrulation, and the development and subdivision of the diencephalon and the midbrain. | Protein atonal homolog 7; Transcription factor involved in the differentiation of retinal ganglion cells. | 0.691 |
otx2b | lhx2b | ENSDARP00000111153 | ENSDARP00000123264 | Homeobox protein OTX2; May play a role in very early embryogenesis, gastrulation, and the development and subdivision of the diencephalon and the midbrain. | LIM homeobox 2b. | 0.453 |
otx2b | pax6a | ENSDARP00000111153 | ENSDARP00000135767 | Homeobox protein OTX2; May play a role in very early embryogenesis, gastrulation, and the development and subdivision of the diencephalon and the midbrain. | Paired box protein Pax-6; Transcription factor expressed in spatially restricted regions of the neural tube during embryonic development; Belongs to the paired homeobox family. | 0.526 |
otx2b | shha | ENSDARP00000111153 | ENSDARP00000125090 | Homeobox protein OTX2; May play a role in very early embryogenesis, gastrulation, and the development and subdivision of the diencephalon and the midbrain. | Sonic hedgehog protein A N-product; Sonic hedgehog protein: The C-terminal part of the sonic hedgehog protein precursor displays an autoproteolysis and a cholesterol transferase activity (By similarity). Both activities result in the cleavage of the full-length protein into two parts (ShhN and ShhC) followed by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated ShhN (By similarity). Both activities occur in the reticulum endoplasmic (By similarity). Once cleaved, ShhC is degraded in the endoplasmic reticulum (By similarity). | 0.852 |