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por protein (Danio rerio) - STRING interaction network
"por" - P450 in Danio rerio
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
porP450 (cytochrome) oxidoreductase; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family (674 aa)    
Predicted Functional Partners:
cyb5a
Cytochrome b5 type A (microsomal) (137 aa)
     
 
  0.849
fancc
Fanconi anemia, complementation group C (554 aa)
       
 
  0.802
cyb5r1
Cytochrome b5 reductase 1; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family (304 aa)
   
 
  0.788
cyb5r3
Cytochrome b5 reductase 3; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family (298 aa)
   
 
  0.765
zgc:63602
Cytochrome P450, family 46, subfamily A, polypeptide 2 (444 aa)
   
 
  0.756
cyp17a1
Cytochrome P450, family 17, subfamily A, polypeptide 1 (519 aa)
     
 
  0.728
cyb5r2
NADH-cytochrome b5 reductase 2; NADH-cytochrome b5 reductases are involved in desaturation and elongation of fatty acids, cholesterol biosynthesis and drug metabolism; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family (309 aa)
   
 
  0.713
cyp51
Lanosterol 14-alpha demethylase; Catalyzes C14-demethylation of lanosterol; it transforms lanosterol into 4,4’-dimethyl cholesta-8,14,24-triene-3-beta-ol (499 aa)
   
 
  0.698
decr1
2,4-dienoyl CoA reductase 1, mitochondrial (333 aa)
     
   
  0.691
derl2
Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome (239 aa)
     
      0.688
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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