STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
poraNADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (674 aa)    
Predicted Functional Partners:
cyp46a1.2
Cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 2.
 
 
 
 0.896
cyp46a1.1
Cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 1; Belongs to the cytochrome P450 family.
 
  
 
 0.874
flad1
Molybdenum cofactor biosynthesis protein-like region; Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme; In the N-terminal section; belongs to the MoaB/Mog family.
  
 
 0.835
fancc
FA complementation group C.
    
 
 0.823
cbsa
Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
 
 
 0.711
cbsb
Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
 
 
 0.711
zgc:123299
Zgc:123299.
 
  
 
 0.681
cyp46a1.4
Cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 4.
 
  
 
 0.678
ciapin1
Anamorsin; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electron [...]
   
 
 0.670
cyb5b
Cytochrome b5 type B; Belongs to the cytochrome b5 family.
   
 
 0.638
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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