STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
slc6a9Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (653 aa)    
Predicted Functional Partners:
glrbb
Glycine receptor beta subunit 2; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
   
  
 0.808
glrba
Glycine receptor betaZ subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
   
  
 0.746
glra3
Glycine receptor, alpha 3; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
   
  
 0.723
glra1
Glycine receptor subunit alphaZ1; Glycine receptors are ligand-gated chloride channels. Channel opening is triggered by extracellular glycine. Plays an important role in the down-regulation of neuronal excitability. Contributes to the generation of inhibitory postsynaptic currents. Channel activity is potentiated by ethanol (By similarity); Belongs to the ligand-gated ion channel (TC 1.A.9) family. Glycine receptor (TC 1.A.9.3) subfamily. GLRA1 sub-subfamily.
   
  
 0.669
slc32a1
Solute carrier family 32 (GABA vesicular transporter), member 1.
   
  
 0.658
gad1b
Glutamate decarboxylase 1b.
  
  
 0.651
glra4a
Glycine receptor, alpha 4a; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
   
  
 0.648
chata
Choline O-acetyltransferase; Catalyzes the reversible synthesis of acetylcholine (ACh) from acetyl CoA and choline at cholinergic synapses. Belongs to the carnitine/choline acetyltransferase family.
      
 0.620
ccdc85al
Coiled-coil domain-containing 85A,-like.
      
 0.600
vsx2
Visual system homeobox 2; Acts as a transcriptional regulator (By similarity). Mediates the differentiation of V2a interneurons (By similarity). Plays a role in eye development and organization of the neuroretina.
   
  
 0.599
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.