STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
l3mbtl2L3MBTL histone methyl-lysine-binding protein 2. (805 aa)    
Predicted Functional Partners:
Q29RF1_DANRE
Si:ch211-195d17.2 protein.
    
 
 0.938
wdr5
WD repeat domain 5.
    
 
 0.928
yy1a
YY1 transcription factor a.
    
 
 0.916
rybpa
RING1 and YY1-binding protein A; May be implicated in the regulation of the transcription as a repressor of the transcriptional activity of E4TF1.
   
 
 0.911
pcgf6
Polycomb group ring finger 6.
   
 
 0.910
rnf2
E3 ubiquitin-protein ligase RING2; E3 ubiquitin-protein ligase that mediates monoubiquitination of 'Lys-119' of histone H2A (H2AK119Ub), thereby playing a central role in histone code and gene regulation. H2AK119Ub gives a specific tag for epigenetic transcriptional repression. Essential component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, rendering chromatin he [...]
    
 
 0.903
cbx3a
Chromobox homolog 3a (HP1 gamma homolog, Drosophila).
    
 
 0.851
yy1b
YY1 transcription factor b.
    
 
 0.845
yaf2
YY1-associated factor 2.
    
 
 0.831
rybpb
RING1 and YY1-binding protein B; May be implicated in the regulation of the transcription as a repressor of the transcriptional activity of E4TF1.
   
 
 0.804
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.