node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ccz1 | mon1a | ENSDARP00000073520 | ENSDARP00000102772 | Vacuolar fusion protein CCZ1 homolog. | MON1 secretory-trafficking family member A. | 0.985 |
ccz1 | mon1bb | ENSDARP00000073520 | ENSDARP00000098438 | Vacuolar fusion protein CCZ1 homolog. | MON1 secretory-trafficking family member Bb. | 0.950 |
ccz1 | rmc1 | ENSDARP00000073520 | ENSDARP00000050825 | Vacuolar fusion protein CCZ1 homolog. | Regulator of MON1-CCZ1. | 0.949 |
ccz1 | vps11 | ENSDARP00000073520 | ENSDARP00000052786 | Vacuolar fusion protein CCZ1 homolog. | Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family. | 0.990 |
ccz1 | vps16 | ENSDARP00000073520 | ENSDARP00000078255 | Vacuolar fusion protein CCZ1 homolog. | Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family. | 0.984 |
ccz1 | vps18 | ENSDARP00000073520 | ENSDARP00000094129 | Vacuolar fusion protein CCZ1 homolog. | Vacuolar protein sorting-associated protein 18 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways. Believed to act as a core component of the putative HOPS endosomal tethering complex which is proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion (By similarity). May be involved in vesicle trafficking to the hepatocyte apical membrane and p [...] | 0.988 |
ccz1 | vps33a | ENSDARP00000073520 | ENSDARP00000133149 | Vacuolar fusion protein CCZ1 homolog. | VPS33A core subunit of CORVET and HOPS complexes; Belongs to the STXBP/unc-18/SEC1 family. | 0.963 |
ccz1 | vps33b | ENSDARP00000073520 | ENSDARP00000065867 | Vacuolar fusion protein CCZ1 homolog. | Vacuolar protein sorting-associated protein 33B; May play a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking/fusion reactions of late endosomes/lysosomes. Mediates phagolysosomal fusion in macrophages. Proposed to be involved in endosomal maturation implicating vipas39. In epithelial cells, the vps33b:vipas39 complex may play a role in the apical recycling pathway and in the maintenance of the apical- basolateral polarity (By similarity). Plays a role in bile duct development. ECO:0000250|UniProtKB:Q9H267, ; Belongs to the STXBP/unc-18/SEC1 [...] | 0.948 |
ccz1 | vps39 | ENSDARP00000073520 | ENSDARP00000100792 | Vacuolar fusion protein CCZ1 homolog. | VPS39 subunit of HOPS complex. | 0.993 |
ccz1 | vps41 | ENSDARP00000073520 | ENSDARP00000116849 | Vacuolar fusion protein CCZ1 homolog. | Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family. | 0.972 |
mon1a | ccz1 | ENSDARP00000102772 | ENSDARP00000073520 | MON1 secretory-trafficking family member A. | Vacuolar fusion protein CCZ1 homolog. | 0.985 |
mon1a | vps11 | ENSDARP00000102772 | ENSDARP00000052786 | MON1 secretory-trafficking family member A. | Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family. | 0.569 |
mon1a | vps16 | ENSDARP00000102772 | ENSDARP00000078255 | MON1 secretory-trafficking family member A. | Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family. | 0.421 |
mon1a | vps18 | ENSDARP00000102772 | ENSDARP00000094129 | MON1 secretory-trafficking family member A. | Vacuolar protein sorting-associated protein 18 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways. Believed to act as a core component of the putative HOPS endosomal tethering complex which is proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion (By similarity). May be involved in vesicle trafficking to the hepatocyte apical membrane and p [...] | 0.475 |
mon1a | vps39 | ENSDARP00000102772 | ENSDARP00000100792 | MON1 secretory-trafficking family member A. | VPS39 subunit of HOPS complex. | 0.563 |
mon1a | vps41 | ENSDARP00000102772 | ENSDARP00000116849 | MON1 secretory-trafficking family member A. | Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family. | 0.815 |
mon1bb | ccz1 | ENSDARP00000098438 | ENSDARP00000073520 | MON1 secretory-trafficking family member Bb. | Vacuolar fusion protein CCZ1 homolog. | 0.950 |
mon1bb | vps11 | ENSDARP00000098438 | ENSDARP00000052786 | MON1 secretory-trafficking family member Bb. | Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family. | 0.570 |
mon1bb | vps16 | ENSDARP00000098438 | ENSDARP00000078255 | MON1 secretory-trafficking family member Bb. | Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family. | 0.423 |
mon1bb | vps18 | ENSDARP00000098438 | ENSDARP00000094129 | MON1 secretory-trafficking family member Bb. | Vacuolar protein sorting-associated protein 18 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways. Believed to act as a core component of the putative HOPS endosomal tethering complex which is proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion (By similarity). May be involved in vesicle trafficking to the hepatocyte apical membrane and p [...] | 0.475 |