STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ext2Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (719 aa)    
Predicted Functional Partners:
ext1a
Exostosin-1a; Glycosyltransferase required for the biosynthesis of heparan- sulfate.
    
0.983
slc35b2
Solute carrier family 35, member B2.
   
  
 0.965
ndst1b
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1b.
    
 
 0.960
uxs1
UDP-glucuronic acid decarboxylase 1; Catalyzes the NAD-dependent decarboxylation of UDP-glucuronic acid to UDP-xylose. Necessary for the biosynthesis of the core tetrasaccharide in glycosaminoglycan biosynthesis (By similarity). Essential during embryogenesis for craniofacial development. Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
      
 0.874
gpc4
Glypican 4; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
     
 0.844
hs2st1a
Heparan sulfate 2-O-sulfotransferase 1a.
   
  
 0.840
ext1b
Exostosin-1b; Glycosyltransferase required for the biosynthesis of heparan- sulfate.
    
 
0.839
ndst2b
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2b.
    
 
 0.814
LOC108179064
Exostosin-1c; Glycosyltransferase required for the biosynthesis of heparan- sulfate.
    
 
0.806
b3gat3
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family.
      
 0.780
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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