node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
XPO5 | dbr1 | ENSDARP00000136252 | ENSDARP00000073957 | Si:ch211-233m11.2. | Lariat debranching enzyme; Cleaves the 2'-5' phosphodiester linkage at the branch point of lariat intron pre-mRNAs after splicing and converts them into linear molecules that are subsequently degraded. It thereby facilitates ribonucleotide turnover. It may also participate in retrovirus replication via an RNA lariat intermediate in cDNA synthesis (By similarity); Belongs to the lariat debranching enzyme family. | 0.646 |
XPO5 | dicer1 | ENSDARP00000136252 | ENSDARP00000045880 | Si:ch211-233m11.2. | Endoribonuclease Dicer; Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short dsRNA-mediated post-transcriptional gene silencing. Cleaves naturally occurring long dsRNAs and short hairpin pre-microRNAs (miRNA) into fragments of twenty-one to twenty-three nucleotides with 3' overhang of two nucleotides, producing respectively short interfering RNAs (siRNA) and mature microRNAs. SiRNAs and miRNAs serve as guide to direct the RNA-induced silencing complex (RISC) to complementary RNAs to degrade them or prevent their translation. Gene silencing mediated by siRNAs, al [...] | 0.885 |
XPO5 | drosha | ENSDARP00000136252 | ENSDARP00000083450 | Si:ch211-233m11.2. | Drosha ribonuclease III. | 0.999 |
cwf19l1 | dbr1 | ENSDARP00000010750 | ENSDARP00000073957 | CWF19-like protein 1. | Lariat debranching enzyme; Cleaves the 2'-5' phosphodiester linkage at the branch point of lariat intron pre-mRNAs after splicing and converts them into linear molecules that are subsequently degraded. It thereby facilitates ribonucleotide turnover. It may also participate in retrovirus replication via an RNA lariat intermediate in cDNA synthesis (By similarity); Belongs to the lariat debranching enzyme family. | 0.801 |
cwf19l1 | xab2 | ENSDARP00000010750 | ENSDARP00000010070 | CWF19-like protein 1. | Similar to Xab2 protein. | 0.729 |
dbr1 | XPO5 | ENSDARP00000073957 | ENSDARP00000136252 | Lariat debranching enzyme; Cleaves the 2'-5' phosphodiester linkage at the branch point of lariat intron pre-mRNAs after splicing and converts them into linear molecules that are subsequently degraded. It thereby facilitates ribonucleotide turnover. It may also participate in retrovirus replication via an RNA lariat intermediate in cDNA synthesis (By similarity); Belongs to the lariat debranching enzyme family. | Si:ch211-233m11.2. | 0.646 |
dbr1 | cwf19l1 | ENSDARP00000073957 | ENSDARP00000010750 | Lariat debranching enzyme; Cleaves the 2'-5' phosphodiester linkage at the branch point of lariat intron pre-mRNAs after splicing and converts them into linear molecules that are subsequently degraded. It thereby facilitates ribonucleotide turnover. It may also participate in retrovirus replication via an RNA lariat intermediate in cDNA synthesis (By similarity); Belongs to the lariat debranching enzyme family. | CWF19-like protein 1. | 0.801 |
dbr1 | dhx38 | ENSDARP00000073957 | ENSDARP00000131918 | Lariat debranching enzyme; Cleaves the 2'-5' phosphodiester linkage at the branch point of lariat intron pre-mRNAs after splicing and converts them into linear molecules that are subsequently degraded. It thereby facilitates ribonucleotide turnover. It may also participate in retrovirus replication via an RNA lariat intermediate in cDNA synthesis (By similarity); Belongs to the lariat debranching enzyme family. | DEAH (Asp-Glu-Ala-His) box polypeptide 38. | 0.875 |
dbr1 | dicer1 | ENSDARP00000073957 | ENSDARP00000045880 | Lariat debranching enzyme; Cleaves the 2'-5' phosphodiester linkage at the branch point of lariat intron pre-mRNAs after splicing and converts them into linear molecules that are subsequently degraded. It thereby facilitates ribonucleotide turnover. It may also participate in retrovirus replication via an RNA lariat intermediate in cDNA synthesis (By similarity); Belongs to the lariat debranching enzyme family. | Endoribonuclease Dicer; Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short dsRNA-mediated post-transcriptional gene silencing. Cleaves naturally occurring long dsRNAs and short hairpin pre-microRNAs (miRNA) into fragments of twenty-one to twenty-three nucleotides with 3' overhang of two nucleotides, producing respectively short interfering RNAs (siRNA) and mature microRNAs. SiRNAs and miRNAs serve as guide to direct the RNA-induced silencing complex (RISC) to complementary RNAs to degrade them or prevent their translation. Gene silencing mediated by siRNAs, al [...] | 0.586 |
dbr1 | drosha | ENSDARP00000073957 | ENSDARP00000083450 | Lariat debranching enzyme; Cleaves the 2'-5' phosphodiester linkage at the branch point of lariat intron pre-mRNAs after splicing and converts them into linear molecules that are subsequently degraded. It thereby facilitates ribonucleotide turnover. It may also participate in retrovirus replication via an RNA lariat intermediate in cDNA synthesis (By similarity); Belongs to the lariat debranching enzyme family. | Drosha ribonuclease III. | 0.708 |
dbr1 | nme8 | ENSDARP00000073957 | ENSDARP00000130661 | Lariat debranching enzyme; Cleaves the 2'-5' phosphodiester linkage at the branch point of lariat intron pre-mRNAs after splicing and converts them into linear molecules that are subsequently degraded. It thereby facilitates ribonucleotide turnover. It may also participate in retrovirus replication via an RNA lariat intermediate in cDNA synthesis (By similarity); Belongs to the lariat debranching enzyme family. | NME/NM23 family member 8; Belongs to the NDK family. | 0.588 |
dbr1 | prpf18 | ENSDARP00000073957 | ENSDARP00000075597 | Lariat debranching enzyme; Cleaves the 2'-5' phosphodiester linkage at the branch point of lariat intron pre-mRNAs after splicing and converts them into linear molecules that are subsequently degraded. It thereby facilitates ribonucleotide turnover. It may also participate in retrovirus replication via an RNA lariat intermediate in cDNA synthesis (By similarity); Belongs to the lariat debranching enzyme family. | Pre-mRNA-splicing factor 18; Participates in the second step of pre-mRNA splicing. | 0.613 |
dbr1 | snrpc | ENSDARP00000073957 | ENSDARP00000010253 | Lariat debranching enzyme; Cleaves the 2'-5' phosphodiester linkage at the branch point of lariat intron pre-mRNAs after splicing and converts them into linear molecules that are subsequently degraded. It thereby facilitates ribonucleotide turnover. It may also participate in retrovirus replication via an RNA lariat intermediate in cDNA synthesis (By similarity); Belongs to the lariat debranching enzyme family. | U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. snrpc/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] | 0.715 |
dbr1 | tardbp | ENSDARP00000073957 | ENSDARP00000058554 | Lariat debranching enzyme; Cleaves the 2'-5' phosphodiester linkage at the branch point of lariat intron pre-mRNAs after splicing and converts them into linear molecules that are subsequently degraded. It thereby facilitates ribonucleotide turnover. It may also participate in retrovirus replication via an RNA lariat intermediate in cDNA synthesis (By similarity); Belongs to the lariat debranching enzyme family. | TAR DNA-binding protein. | 0.579 |
dbr1 | xab2 | ENSDARP00000073957 | ENSDARP00000010070 | Lariat debranching enzyme; Cleaves the 2'-5' phosphodiester linkage at the branch point of lariat intron pre-mRNAs after splicing and converts them into linear molecules that are subsequently degraded. It thereby facilitates ribonucleotide turnover. It may also participate in retrovirus replication via an RNA lariat intermediate in cDNA synthesis (By similarity); Belongs to the lariat debranching enzyme family. | Similar to Xab2 protein. | 0.579 |
dhx38 | dbr1 | ENSDARP00000131918 | ENSDARP00000073957 | DEAH (Asp-Glu-Ala-His) box polypeptide 38. | Lariat debranching enzyme; Cleaves the 2'-5' phosphodiester linkage at the branch point of lariat intron pre-mRNAs after splicing and converts them into linear molecules that are subsequently degraded. It thereby facilitates ribonucleotide turnover. It may also participate in retrovirus replication via an RNA lariat intermediate in cDNA synthesis (By similarity); Belongs to the lariat debranching enzyme family. | 0.875 |
dhx38 | prpf18 | ENSDARP00000131918 | ENSDARP00000075597 | DEAH (Asp-Glu-Ala-His) box polypeptide 38. | Pre-mRNA-splicing factor 18; Participates in the second step of pre-mRNA splicing. | 0.876 |
dhx38 | snrpc | ENSDARP00000131918 | ENSDARP00000010253 | DEAH (Asp-Glu-Ala-His) box polypeptide 38. | U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. snrpc/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] | 0.588 |
dhx38 | xab2 | ENSDARP00000131918 | ENSDARP00000010070 | DEAH (Asp-Glu-Ala-His) box polypeptide 38. | Similar to Xab2 protein. | 0.989 |
dicer1 | XPO5 | ENSDARP00000045880 | ENSDARP00000136252 | Endoribonuclease Dicer; Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short dsRNA-mediated post-transcriptional gene silencing. Cleaves naturally occurring long dsRNAs and short hairpin pre-microRNAs (miRNA) into fragments of twenty-one to twenty-three nucleotides with 3' overhang of two nucleotides, producing respectively short interfering RNAs (siRNA) and mature microRNAs. SiRNAs and miRNAs serve as guide to direct the RNA-induced silencing complex (RISC) to complementary RNAs to degrade them or prevent their translation. Gene silencing mediated by siRNAs, al [...] | Si:ch211-233m11.2. | 0.885 |