STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
htr7a5-hydroxytryptamine (serotonin) receptor 7a; Belongs to the G-protein coupled receptor 1 family. (479 aa)    
Predicted Functional Partners:
htr3b
5-hydroxytryptamine (serotonin) receptor 3B; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
      
 0.841
gnal
Guanine nucleotide-binding protein G(olf) subunit alpha.
    
 0.778
Gnal2
Uncharacterized protein.
    
 0.778
htr3a
5-hydroxytryptamine (serotonin) receptor 3A; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
      
 0.748
grm4
Glutamate receptor, metabotropic 4.
    
 
 0.565
si:dkey-6b12.5
Si:dkey-6b12.5.
    
  0.525
tph1a
Tryptophan hydroxylase 1 (tryptophan 5-monooxygenase) a.
      
 0.505
slc6a4b
Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
    
 
 0.500
ptger3
Prostaglandin E receptor 3 (subtype EP3).
      
 0.474
f2rl2
Coagulation factor II (thrombin) receptor-like 2.
    
 
 0.474
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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