STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kcnk7Potassium channel, subfamily K, member 7; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (342 aa)    
Predicted Functional Partners:
slc25a45
Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.895
fam89b
Family with sequence similarity 89 member B.
      
 0.861
cdc42ep2
CDC42 effector protein (Rho GTPase-binding) 2.
      
 0.854
znrd2
Zinc ribbon domain-containing 2.
      
 0.834
MAP3K11
Si:cabz01078036.1.
 
    
 0.807
frmd8
FERM domain-containing protein 8; Promotes the cell surface stability of rhomboid 5 homologs and prevents their degradation via the endolysosomal pathway. By acting on rhomboid 5 homologs, involved in ADAM17-mediated ligand shedding (By similarity). Negatively regulates the Wnt/beta-catenin signaling pathway.
      
 0.802
dpf2
D4, zinc and double PHD fingers family 2.
      
 0.717
kcnk2a
Potassium channel, subfamily K, member 2a; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
     
0.624
kcnk4a
Potassium channel, subfamily K, member 4a; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
     
0.622
ltbp3
Latent transforming growth factor beta binding protein 3.
    
 
 0.545
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.