STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hellsHelicase, lymphoid-specific (853 aa)    
Predicted Functional Partners:
bptf
Bromodomain PHD finger transcription factor
   
 
 0.968
mcm5
DNA helicase; MCM5 minichromosome maintenance deficient 5 (S. cerevisiae); Belongs to the MCM family
   
 
 0.957
mcm2
DNA helicase; MCM2 minichromosome maintenance deficient 2, mitotin (S. cerevisiae); Belongs to the MCM family
   
 
 0.947
cdca7a
Cell division cycle associated 7a
   
 
 0.939
cdc5l
CDC5 cell division cycle 5-like (S. pombe)
   
 
 0.918
ENSDARG00000024204
DNA helicase; MCM3 minichromosome maintenance deficient 3 (S. cerevisiae); Belongs to the MCM family
   
 
 0.870
mcm4
DNA helicase; MCM4 minichromosome maintenance deficient 4, mitotin (S. cerevisiae); Belongs to the MCM family
   
 
 0.847
kif11
Kinesin family member 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family
   
 
 0.842
cdk1
Cell division control protein 2; Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily
   
 
 0.837
ENSDARG00000091448
Ubiquitin-like, containing PHD and RING finger domains, 1
  
 
 0.818
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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