STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hgdHomogentisate 1,2-dioxygenase. (443 aa)    
Predicted Functional Partners:
hpda
4-hydroxyphenylpyruvate dioxygenase; Key enzyme in the degradation of tyrosine; Belongs to the 4HPPD family.
  
 0.999
hpdb
4-hydroxyphenylpyruvate dioxygenase.
  
 0.998
gstz1
Glutathione S-transferase zeta 1; Belongs to the GST superfamily.
 
 
 0.997
HPDL
4-hydroxyphenylpyruvate dioxygenase.
  
 0.984
hpdl
4-hydroxyphenylpyruvate dioxygenase.
  
 0.983
fah
Fumarylacetoacetase.
 
 0.953
pcbd1
Pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha.
  
  
 0.872
fahd1
Fumarylacetoacetate hydrolase domain-containing 1.
  
 
 0.862
fahd2a
Fumarylacetoacetate hydrolase domain-containing 2A.
  
 
 0.860
agxt2
Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
   
  
 0.833
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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