node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
esco2 | espl1 | ENSDARP00000002535 | ENSDARP00000128879 | N-acetyltransferase ESCO2; Acetyltransferase required for the establishment of sister chromatid cohesion. Couples the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together (By similarity). Essential for early development. | Extra spindle pole bodies-like 1, separase. | 0.873 |
esco2 | nipblb | ENSDARP00000002535 | ENSDARP00000081295 | N-acetyltransferase ESCO2; Acetyltransferase required for the establishment of sister chromatid cohesion. Couples the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together (By similarity). Essential for early development. | Nipped-B-like protein B; May play a structural role in chromatin. Involved in sister chromatid cohesion, possibly by facilitating the cohesin complex loading. Transcription factor, which may promote cortical neuron migration during brain development by regulating the transcription of crucial genes in this process (By similarity). | 0.951 |
esco2 | pds5a | ENSDARP00000002535 | ENSDARP00000109877 | N-acetyltransferase ESCO2; Acetyltransferase required for the establishment of sister chromatid cohesion. Couples the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together (By similarity). Essential for early development. | Sister chromatid cohesion protein PDS5 homolog A; May regulate sister chromatid cohesion during mitosis and couple it to DNA replication. | 0.921 |
esco2 | pds5b | ENSDARP00000002535 | ENSDARP00000136712 | N-acetyltransferase ESCO2; Acetyltransferase required for the establishment of sister chromatid cohesion. Couples the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together (By similarity). Essential for early development. | PDS5 cohesin-associated factor B. | 0.951 |
esco2 | rad21a | ENSDARP00000002535 | ENSDARP00000009867 | N-acetyltransferase ESCO2; Acetyltransferase required for the establishment of sister chromatid cohesion. Couples the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together (By similarity). Essential for early development. | Double-strand-break repair protein rad21 homolog A; Double-strand-break repair protein rad21 homolog: As a member of the cohesin complex, involved in sister chromatid cohesion from the time of DNA replication in S phase to their segregation in mitosis, a function that is essential for proper chromosome segregation, post- replicative DNA repair, and the prevention of inappropriate recombination between repetitive regions. The cohesin complex may also play a role in spindle pole assembly during mitosis (By similarity). In interphase, cohesins may function in the control of gene expressio [...] | 0.951 |
esco2 | rad21l1 | ENSDARP00000002535 | ENSDARP00000074083 | N-acetyltransferase ESCO2; Acetyltransferase required for the establishment of sister chromatid cohesion. Couples the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together (By similarity). Essential for early development. | RAD21 cohesin complex component-like 1. | 0.622 |
esco2 | smc1al | ENSDARP00000002535 | ENSDARP00000075459 | N-acetyltransferase ESCO2; Acetyltransferase required for the establishment of sister chromatid cohesion. Couples the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together (By similarity). Essential for early development. | Structural maintenance of chromosomes protein. | 0.961 |
esco2 | smc3 | ENSDARP00000002535 | ENSDARP00000024411 | N-acetyltransferase ESCO2; Acetyltransferase required for the establishment of sister chromatid cohesion. Couples the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together (By similarity). Essential for early development. | Structural maintenance of chromosomes protein. | 0.998 |
esco2 | stag1a | ENSDARP00000002535 | ENSDARP00000113547 | N-acetyltransferase ESCO2; Acetyltransferase required for the establishment of sister chromatid cohesion. Couples the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together (By similarity). Essential for early development. | Stromal antigen 1a. | 0.737 |
esco2 | stag2b | ENSDARP00000002535 | ENSDARP00000141467 | N-acetyltransferase ESCO2; Acetyltransferase required for the establishment of sister chromatid cohesion. Couples the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together (By similarity). Essential for early development. | Stromal antigen 2b. | 0.675 |
espl1 | esco2 | ENSDARP00000128879 | ENSDARP00000002535 | Extra spindle pole bodies-like 1, separase. | N-acetyltransferase ESCO2; Acetyltransferase required for the establishment of sister chromatid cohesion. Couples the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together (By similarity). Essential for early development. | 0.873 |
espl1 | nipblb | ENSDARP00000128879 | ENSDARP00000081295 | Extra spindle pole bodies-like 1, separase. | Nipped-B-like protein B; May play a structural role in chromatin. Involved in sister chromatid cohesion, possibly by facilitating the cohesin complex loading. Transcription factor, which may promote cortical neuron migration during brain development by regulating the transcription of crucial genes in this process (By similarity). | 0.880 |
espl1 | pds5a | ENSDARP00000128879 | ENSDARP00000109877 | Extra spindle pole bodies-like 1, separase. | Sister chromatid cohesion protein PDS5 homolog A; May regulate sister chromatid cohesion during mitosis and couple it to DNA replication. | 0.816 |
espl1 | pds5b | ENSDARP00000128879 | ENSDARP00000136712 | Extra spindle pole bodies-like 1, separase. | PDS5 cohesin-associated factor B. | 0.895 |
espl1 | rad21a | ENSDARP00000128879 | ENSDARP00000009867 | Extra spindle pole bodies-like 1, separase. | Double-strand-break repair protein rad21 homolog A; Double-strand-break repair protein rad21 homolog: As a member of the cohesin complex, involved in sister chromatid cohesion from the time of DNA replication in S phase to their segregation in mitosis, a function that is essential for proper chromosome segregation, post- replicative DNA repair, and the prevention of inappropriate recombination between repetitive regions. The cohesin complex may also play a role in spindle pole assembly during mitosis (By similarity). In interphase, cohesins may function in the control of gene expressio [...] | 0.991 |
espl1 | rad21l1 | ENSDARP00000128879 | ENSDARP00000074083 | Extra spindle pole bodies-like 1, separase. | RAD21 cohesin complex component-like 1. | 0.969 |
espl1 | smc1al | ENSDARP00000128879 | ENSDARP00000075459 | Extra spindle pole bodies-like 1, separase. | Structural maintenance of chromosomes protein. | 0.987 |
espl1 | smc3 | ENSDARP00000128879 | ENSDARP00000024411 | Extra spindle pole bodies-like 1, separase. | Structural maintenance of chromosomes protein. | 0.995 |
espl1 | stag1a | ENSDARP00000128879 | ENSDARP00000113547 | Extra spindle pole bodies-like 1, separase. | Stromal antigen 1a. | 0.959 |
espl1 | stag2b | ENSDARP00000128879 | ENSDARP00000141467 | Extra spindle pole bodies-like 1, separase. | Stromal antigen 2b. | 0.941 |