STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
plk1Serine/threonine-protein kinase PLK. (595 aa)    
Predicted Functional Partners:
ccnb1
Cyclin B1; Belongs to the cyclin family.
   
 0.998
cdc20
Cell division cycle 20 homolog.
   
 0.993
cdc25b
Cell division cycle 25B.
   
 0.989
espl1
Extra spindle pole bodies-like 1, separase.
   
 0.989
ccnb2
Cyclin B2; Belongs to the cyclin family.
   
 0.988
ccnb3
Cyclin B3; Belongs to the cyclin family.
   
 0.983
pcnt
Pericentrin.
   
 0.979
cdk1
Cell division control protein 2; Belongs to the protein kinase superfamily.
   
0.975
incenp
Uncharacterized protein.
   
 0.974
bora
Protein aurora borealis; Required for the activation of aurka at the onset of mitosis.
   
 0.969
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.