STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSDARG00000058738Si:ch211-117c9.2; Solute carrier family 26 (anion exchanger), member 6 (786 aa)    
Predicted Functional Partners:
celsr3
Cadherin, EGF LAG seven-pass G-type receptor 3
 
    
 0.574
commd3
COMM domain containing 3
      
 0.563
ahcyl1
Adenosylhomocysteinase; S-adenosylhomocysteine hydrolase-like 1
   
  
 0.553
SLC4A7
Anion exchange protein; Solute carrier family 4, sodium bicarbonate cotransporter, member 7
      
 0.545
cftr
Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]
   
 
 0.538
pdzk1
PDZ domain containing 1
   
 
 0.515
ENSDARG00000053124
Si:dkey-148a17.6; Belongs to the G-protein coupled receptor 1 family
      
 0.513
slc34a1a
Solute carrier family 34 (sodium phosphate), member 1a
   
  
 0.498
nphs2
Nephrosis 2, idiopathic, steroid-resistant (podocin)
   
    0.491
abcc4
ATP-binding cassette, sub-family C (CFTR/MRP), member 4
   
 
 0.482
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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