node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cpz | spcs1 | ENSDARP00000150019 | ENSDARP00000076814 | Carboxypeptidase Z. | Signal peptidase complex subunit 1 homolog (S. cerevisiae). | 0.850 |
dad1 | grp | ENSDARP00000132059 | ENSDARP00000063243 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...] | Gastrin-releasing peptide. | 0.435 |
dad1 | sec11a | ENSDARP00000132059 | ENSDARP00000009538 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...] | Signal peptidase complex catalytic subunit SEC11. | 0.453 |
dad1 | sec63 | ENSDARP00000132059 | ENSDARP00000006629 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...] | SEC63 homolog, protein translocation regulator. | 0.717 |
dad1 | spcs1 | ENSDARP00000132059 | ENSDARP00000076814 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...] | Signal peptidase complex subunit 1 homolog (S. cerevisiae). | 0.833 |
dad1 | spcs2 | ENSDARP00000132059 | ENSDARP00000113444 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...] | Probable signal peptidase complex subunit 2; Microsomal signal peptidase is a membrane-bound endoproteinase that removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. | 0.738 |
dad1 | spcs3 | ENSDARP00000132059 | ENSDARP00000139098 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...] | Signal peptidase complex subunit 3. | 0.546 |
dad1 | srp9 | ENSDARP00000132059 | ENSDARP00000124362 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...] | Signal recognition particle 9 kDa protein; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding. | 0.514 |
grp | dad1 | ENSDARP00000063243 | ENSDARP00000132059 | Gastrin-releasing peptide. | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...] | 0.435 |
grp | spcs1 | ENSDARP00000063243 | ENSDARP00000076814 | Gastrin-releasing peptide. | Signal peptidase complex subunit 1 homolog (S. cerevisiae). | 0.926 |
grp | spcs2 | ENSDARP00000063243 | ENSDARP00000113444 | Gastrin-releasing peptide. | Probable signal peptidase complex subunit 2; Microsomal signal peptidase is a membrane-bound endoproteinase that removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. | 0.945 |
grp | spcs3 | ENSDARP00000063243 | ENSDARP00000139098 | Gastrin-releasing peptide. | Signal peptidase complex subunit 3. | 0.921 |
grp | srp54 | ENSDARP00000063243 | ENSDARP00000139136 | Gastrin-releasing peptide. | Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.407 |
sec11a | dad1 | ENSDARP00000009538 | ENSDARP00000132059 | Signal peptidase complex catalytic subunit SEC11. | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...] | 0.453 |
sec11a | sec63 | ENSDARP00000009538 | ENSDARP00000006629 | Signal peptidase complex catalytic subunit SEC11. | SEC63 homolog, protein translocation regulator. | 0.595 |
sec11a | spcs1 | ENSDARP00000009538 | ENSDARP00000076814 | Signal peptidase complex catalytic subunit SEC11. | Signal peptidase complex subunit 1 homolog (S. cerevisiae). | 0.997 |
sec11a | spcs2 | ENSDARP00000009538 | ENSDARP00000113444 | Signal peptidase complex catalytic subunit SEC11. | Probable signal peptidase complex subunit 2; Microsomal signal peptidase is a membrane-bound endoproteinase that removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. | 0.997 |
sec11a | spcs3 | ENSDARP00000009538 | ENSDARP00000139098 | Signal peptidase complex catalytic subunit SEC11. | Signal peptidase complex subunit 3. | 0.984 |
sec11a | srp19 | ENSDARP00000009538 | ENSDARP00000051775 | Signal peptidase complex catalytic subunit SEC11. | Signal recognition particle 19. | 0.813 |
sec11a | srp54 | ENSDARP00000009538 | ENSDARP00000139136 | Signal peptidase complex catalytic subunit SEC11. | Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.729 |