STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
oaz2bOrnithine decarboxylase antizyme 2b. (186 aa)    
Predicted Functional Partners:
odc1
Ornithine decarboxylase 1; Belongs to the Orn/Lys/Arg decarboxylase class-II family.
    
 0.948
azin1a
Antizyme inhibitor 1a; Belongs to the Orn/Lys/Arg decarboxylase class-II family.
    
 
 0.900
azin1b
Antizyme inhibitor 1b; Belongs to the Orn/Lys/Arg decarboxylase class-II family.
   
 0.810
ppp1r3ca
Protein phosphatase 1 regulatory subunit 3C; Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown.
      
 0.742
oaz1a
Ornithine decarboxylase antizyme 1; Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis and uptake in response to increased intracellular polyamine levels. Binds to ODC monomers, inhibiting the assembly of the functional ODC homodimer, and targets the monomers for ubiquitin- independent proteolytic destruction by the 26S proteasome.
  
  
0.507
zbtb1
Zinc finger and BTB domain-containing 1.
      
 0.480
psmb4
Proteasome subunit beta; Belongs to the peptidase T1B family.
   
 0.454
zbtb21
Zinc finger and BTB domain-containing 21.
      
 0.452
rpl19
60S ribosomal protein L19; Belongs to the eukaryotic ribosomal protein eL19 family.
   
  
 0.450
psmd3
Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 3.
   
 
 0.449
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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