STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ubtd1bUbiquitin domain-containing protein 1; May be involved in the regulation of cellular senescence through a positive feedback loop with TP53. (227 aa)    
Predicted Functional Partners:
frmpd2
FERM and PDZ domain-containing 2.
      
 0.865
tmub1
Transmembrane and ubiquitin-like domain-containing protein 1; May contribute to the regulation of translation during cell- cycle progression. May contribute to the regulation of cell proliferation (By similarity). The membrane form is involved in sterol- regulated ubiquitination and degradation of HMG-CoA reductase HMGCR. May be involved in centrosome assembly.
      
 0.830
ubqln4
Ubiquilin 4.
    
 
 0.710
rad23aa
RAD23 homolog A, nucleotide excision repair protein a.
    
 
 0.687
rbck1
RanBP-type and C3HC4-type zinc finger-containing protein 1.
      
 0.680
sf3a1
Novel protein similar to human splicing factor 3a, subunit 1, 120kD (SF3A1).
      
 0.675
usp48
Ubiquitin-specific peptidase 48; Belongs to the peptidase C19 family.
      
 0.661
rad23b
RAD23 homolog B, nucleotide excision repair protein.
    
 
 0.652
herpud1
Homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1.
      
 0.628
shrprbck1r
RanBP-type and C3HC4-type zinc finger-containing protein 1; Component of the LUBAC complex which conjugates linear ('M- 1'-linked) polyubiquitin chains to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation.
      
 0.600
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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