STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
herc4HECT and RLD domain-containing E3 ubiquitin protein ligase 4. (1052 aa)    
Predicted Functional Partners:
uchl5
Ubiquitin carboxyl-terminal hydrolase.
    
 
 0.727
wdfy4
WDFY family member 4.
      
 0.678
sb:cb1081
Si:ch73-252p3.1.
      
 0.669
fam13a
Family with sequence similarity 13 member A.
      
 0.629
tcea2
Transcription elongation factor A (SII), 2.
      
 0.573
kcnc1a
Potassium voltage-gated channel, Shaw-related subfamily, member 1a; Belongs to the potassium channel family.
    
 
 0.572
itih6
Inter-alpha-trypsin inhibitor heavy chain family member 6.
    
 
 0.557
olfch1
Olfactory receptor C family, h1.
      
 0.550
ube2l3a
Ubiquitin-conjugating enzyme E2L 3a; Belongs to the ubiquitin-conjugating enzyme family.
    
 
 0.493
kat6b
Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.
    
 
 0.478
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.