STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nsd1aNuclear receptor-binding SET domain protein 1a. (2071 aa)    
Predicted Functional Partners:
ash1l
Ash1 (absent, small, or homeotic)-like (Drosophila).
   
 
0.728
plod2
Procollagen lysine 2-oxoglutarate 5-dioxygenase 2b isoform.
    
 0.686
plod1a
Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1a.
    
 0.686
plod3
Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3.
    
 0.686
camkmt
Calmodulin-lysine N-methyltransferase.
     
 0.672
zgc:173552
Histone H3; Belongs to the histone H3 family.
   
 0.554
zgc:113983
Histone H3.2; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
   
 0.554
ENSDARP00000147095
Chromo domain-containing protein.
   
 
 0.551
setd2
SET domain-containing 2, histone lysine methyltransferase.
   
  
0.529
zbtb24
Zinc finger and BTB domain-containing protein 24; May be involved in BMP2-induced transcription. Belongs to the krueppel C2H2-type zinc-finger protein family.
   
 
 0.527
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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