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nat15 protein (Danio rerio) - STRING interaction network
"nat15" - N-alpha-acetyltransferase 60 in Danio rerio
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
nat15N-alpha-acetyltransferase 60; N-alpha-acetyltransferase that specifically mediates the acetylation of N-terminal residues of the transmembrane proteins, with a strong preference for N-termini facing the cytosol. Displays N-terminal acetyltransferase activity towards a range of N-terminal sequences including those starting with Met-Lys, Met- Val, Met-Ala and Met-Met. Required for normal chromosomal segregation during anaphase. May also show histone acetyltransferase activity; such results are however unclear in vivo and would require additional experimental evidences (242 aa)    
Predicted Functional Partners:
naa40
N-alpha-acetyltransferase 40; N-alpha-acetyltransferase that specifically mediates the acetylation of the N-terminal residues of histones H4 and H2A. In contrast to other N-alpha-acetyltransferase, has a very specific selectivity for histones H4 and H2A N-terminus and specifically recognizes the ’Ser-Gly-Arg-Gly sequence’; Belongs to the acetyltransferase family. NAA40 subfamily (237 aa)
     
   
  0.973
ENSDARG00000090570
N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae) (137 aa)
     
   
  0.972
naa30
N(alpha)-acetyltransferase 30, NatC catalytic subunit (363 aa)
     
   
  0.962
naa50
N-alpha-acetyltransferase 50; N-alpha-acetyltransferase that acetylates the N-terminus of proteins that retain their initiating methionine (By similarity). Has a broad substrate specificity- able to acetylate the initiator methionine of most peptides, except for those with a proline in second position (By similarity). Also displays N- epsilon-acetyltransferase activity by mediating acetylation of the side chain of specific lysines on proteins (By similarity). The relevance of N-epsilon-acetyltransferase activity is however unclear (By similarity). Required for sister chromatid cohesion [...] (169 aa)
     
   
  0.957
naa20
N-alpha-acetyltransferase 20; Catalytic subunit of the NatB complex which catalyzes acetylation of the N-terminal methionine residues of peptides beginning with Met-Asp, Met-Glu, Met-Asn and Met-Gln. Proteins with cell cycle functions are overrepresented in the pool of NatB substrates. Required for maintaining the structure and function of actomyosin fibers and for proper cellular migration (178 aa)
     
   
  0.927
naa10
N(alpha)-acetyltransferase 10, NatA catalytic subunit (224 aa)
     
 
  0.911
naa15a
N(alpha)-acetyltransferase 15, NatA auxiliary subunit a (867 aa)
     
 
  0.813
naa15b
N(alpha)-acetyltransferase 15, NatA auxiliary subunit b (799 aa)
     
 
  0.813
ccdc101
SAGA complex-associated factor 29; Coiled-coil domain containing 101 (293 aa)
     
 
  0.750
hypk
Huntingtin interacting protein K (121 aa)
     
 
  0.745
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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