STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
adat1Adenosine deaminase tRNA-specific 1. (466 aa)    
Predicted Functional Partners:
adat3
Probable inactive tRNA-specific adenosine deaminase-like protein 3.
      
 0.924
adat2
tRNA-specific adenosine deaminase 2; Probably participates in deamination of adenosine-34 to inosine in many tRNAs; Belongs to the cytidine and deoxycytidylate deaminase family. ADAT2 subfamily.
      
 0.920
kars1
Lysine--tRNA ligase.
 
    
 0.799
slc30a9
Zinc transporter 9; May act as a zinc transporter involved in intracellular zinc homeostasis. May play a role as nuclear receptor coactivator. Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
      
 0.740
ptpa
Serine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
   
  
 0.568
edar
Ectodysplasin A receptor.
      
 0.568
slc24a5
Sodium/potassium/calcium exchanger 5; Cation exchanger which plays a central role in pigmentation, possibly by participating in ion transport in melanosomes. Probably transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+). Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
      
 0.554
ip6k2a
Kinase; Belongs to the inositol phosphokinase (IPK) family.
      
 0.497
ippk
Inositol-pentakisphosphate 2-kinase; Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). InsP6 is involved in many processes such as mRNA export, non-homologous end-joining, endocytosis and ion channel regulation. InsP6 also acts as a key regulator of left- right asymmetry in embryo, probably by regulating asymmetric Ca(2+) during left-right specification.
      
 0.437
ctcf
CCCTC-binding factor (zinc finger protein).
    
 
 0.426
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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