STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
foxred2FAD-dependent oxidoreductase domain-containing protein 2; Probable flavoprotein which may function in endoplasmic reticulum associated degradation (ERAD). May bind non-native proteins in the endoplasmic reticulum and target them to the ubiquitination machinery for subsequent degradation (By similarity); Belongs to the FOXRED2 family. (687 aa)    
Predicted Functional Partners:
txn2
Thioredoxin 2.
 
  
 
 0.805
sel1l
SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.
    
 
 0.740
prpsap1
Phosphoribosyl pyrophosphate synthetase-associated protein 1.
      
 0.739
tom1
Target of myb1 membrane-trafficking protein; Belongs to the TOM1 family.
   
  
 0.707
rasd2
RASD family member 2.
   
 
 0.693
SAMD5
Sterile alpha motif domain containing 5.
    
 
 0.682
txndc16
Thioredoxin domain-containing 16.
    
 
 0.621
nfe2l2b
Nuclear factor, erythroid 2-like 2b.
      
 0.603
nfe2
Nuclear factor, erythroid 2.
      
 0.582
rbfox2
RNA-binding fox-1 homolog 2.
      
 0.581
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (32%) [HD]