STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cacnb4bVoltage-gated calcium channel beta-4 subunit variant 2. (523 aa)    
Predicted Functional Partners:
cacna1ab
Calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, b.
   
 0.862
cacna2d3
Calcium channel, voltage-dependent, alpha2/delta subunit 3.
   
 0.850
CACNA2D3
Calcium voltage-gated channel auxiliary subunit alpha2delta 3.
   
 0.848
cacna1ba
Voltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents.
   
 0.822
kcnab2a
Potassium voltage-gated channel, shaker-related subfamily, beta member 2 a.
   
  
 0.763
cacna2d2a
Calcium channel, voltage-dependent, alpha 2/delta subunit 2a.
   
 0.751
cacng1a
Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics.
   
 0.747
cacng1b
Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics.
   
 0.747
cacna2d1a
Calcium channel, voltage-dependent, alpha 2/delta subunit 1a.
   
 0.746
cacna2d2b
Calcium channel, voltage-dependent, alpha 2/delta subunit 2b.
   
 0.745
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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