node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
casp3a | casp7 | ENSDARP00000006831 | ENSDARP00000127315 | Caspase 3, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family. | Caspase 7, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. | 0.717 |
casp3a | stk24b | ENSDARP00000006831 | ENSDARP00000135203 | Caspase 3, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family. | Serine/threonine kinase 24b (STE20 homolog, yeast). | 0.750 |
casp7 | casp3a | ENSDARP00000127315 | ENSDARP00000006831 | Caspase 7, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. | Caspase 3, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family. | 0.717 |
casp7 | stk24b | ENSDARP00000127315 | ENSDARP00000135203 | Caspase 7, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. | Serine/threonine kinase 24b (STE20 homolog, yeast). | 0.750 |
krit1 | pdcd10a | ENSDARP00000138856 | ENSDARP00000156496 | Krev interaction trapped protein 1; Component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity. Negative regulator of angiogenesis. Inhibits endothelial proliferation, apoptosis, migration, lumen formation and sprouting angiogenesis in primary endothelial cells. Plays a role in integrin signaling. Plays an important role in the maintenance of the intracellular reactive oxygen species (ROS) homeostasis to prevent oxidative cellular damage. Facilitates the down-regulation of cyclin-D1 (CCND1) levels required for cell transition from pr [...] | Programmed cell death protein 10-A; Promotes cell proliferation. Modulates apoptotic pathways. Increases mitogen-activated protein kinase activity. Important for cell migration, and for normal structure and assembly of the Golgi complex. Important for KDR/VEGFR2 signaling. Required for normal angiogenesis, vasculogenesis and hematopoiesis during embryonic development (By similarity). Required for normal cardiovascular development. | 0.983 |
krit1 | stk24b | ENSDARP00000138856 | ENSDARP00000135203 | Krev interaction trapped protein 1; Component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity. Negative regulator of angiogenesis. Inhibits endothelial proliferation, apoptosis, migration, lumen formation and sprouting angiogenesis in primary endothelial cells. Plays a role in integrin signaling. Plays an important role in the maintenance of the intracellular reactive oxygen species (ROS) homeostasis to prevent oxidative cellular damage. Facilitates the down-regulation of cyclin-D1 (CCND1) levels required for cell transition from pr [...] | Serine/threonine kinase 24b (STE20 homolog, yeast). | 0.689 |
krit1 | strip1 | ENSDARP00000138856 | ENSDARP00000103366 | Krev interaction trapped protein 1; Component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity. Negative regulator of angiogenesis. Inhibits endothelial proliferation, apoptosis, migration, lumen formation and sprouting angiogenesis in primary endothelial cells. Plays a role in integrin signaling. Plays an important role in the maintenance of the intracellular reactive oxygen species (ROS) homeostasis to prevent oxidative cellular damage. Facilitates the down-regulation of cyclin-D1 (CCND1) levels required for cell transition from pr [...] | Striatin-interacting protein 1 homolog; May play a role in the regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics and cell shape (By similarity). | 0.665 |
krit1 | strip2 | ENSDARP00000138856 | ENSDARP00000128547 | Krev interaction trapped protein 1; Component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity. Negative regulator of angiogenesis. Inhibits endothelial proliferation, apoptosis, migration, lumen formation and sprouting angiogenesis in primary endothelial cells. Plays a role in integrin signaling. Plays an important role in the maintenance of the intracellular reactive oxygen species (ROS) homeostasis to prevent oxidative cellular damage. Facilitates the down-regulation of cyclin-D1 (CCND1) levels required for cell transition from pr [...] | Striatin-interacting protein 2. | 0.564 |
krit1 | strn | ENSDARP00000138856 | ENSDARP00000139359 | Krev interaction trapped protein 1; Component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity. Negative regulator of angiogenesis. Inhibits endothelial proliferation, apoptosis, migration, lumen formation and sprouting angiogenesis in primary endothelial cells. Plays a role in integrin signaling. Plays an important role in the maintenance of the intracellular reactive oxygen species (ROS) homeostasis to prevent oxidative cellular damage. Facilitates the down-regulation of cyclin-D1 (CCND1) levels required for cell transition from pr [...] | Striatin, calmodulin-binding protein. | 0.636 |
lrsam1 | stk24b | ENSDARP00000080204 | ENSDARP00000135203 | Leucine-rich repeat and sterile alpha motif-containing 1. | Serine/threonine kinase 24b (STE20 homolog, yeast). | 0.648 |
mob4 | pdcd10a | ENSDARP00000072975 | ENSDARP00000156496 | MOB1, Mps One Binder kinase activator-like 3 (Yeast). | Programmed cell death protein 10-A; Promotes cell proliferation. Modulates apoptotic pathways. Increases mitogen-activated protein kinase activity. Important for cell migration, and for normal structure and assembly of the Golgi complex. Important for KDR/VEGFR2 signaling. Required for normal angiogenesis, vasculogenesis and hematopoiesis during embryonic development (By similarity). Required for normal cardiovascular development. | 0.848 |
mob4 | stk24b | ENSDARP00000072975 | ENSDARP00000135203 | MOB1, Mps One Binder kinase activator-like 3 (Yeast). | Serine/threonine kinase 24b (STE20 homolog, yeast). | 0.656 |
mob4 | strip1 | ENSDARP00000072975 | ENSDARP00000103366 | MOB1, Mps One Binder kinase activator-like 3 (Yeast). | Striatin-interacting protein 1 homolog; May play a role in the regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics and cell shape (By similarity). | 0.861 |
mob4 | strip2 | ENSDARP00000072975 | ENSDARP00000128547 | MOB1, Mps One Binder kinase activator-like 3 (Yeast). | Striatin-interacting protein 2. | 0.859 |
mob4 | strn | ENSDARP00000072975 | ENSDARP00000139359 | MOB1, Mps One Binder kinase activator-like 3 (Yeast). | Striatin, calmodulin-binding protein. | 0.825 |
pdcd10a | krit1 | ENSDARP00000156496 | ENSDARP00000138856 | Programmed cell death protein 10-A; Promotes cell proliferation. Modulates apoptotic pathways. Increases mitogen-activated protein kinase activity. Important for cell migration, and for normal structure and assembly of the Golgi complex. Important for KDR/VEGFR2 signaling. Required for normal angiogenesis, vasculogenesis and hematopoiesis during embryonic development (By similarity). Required for normal cardiovascular development. | Krev interaction trapped protein 1; Component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity. Negative regulator of angiogenesis. Inhibits endothelial proliferation, apoptosis, migration, lumen formation and sprouting angiogenesis in primary endothelial cells. Plays a role in integrin signaling. Plays an important role in the maintenance of the intracellular reactive oxygen species (ROS) homeostasis to prevent oxidative cellular damage. Facilitates the down-regulation of cyclin-D1 (CCND1) levels required for cell transition from pr [...] | 0.983 |
pdcd10a | mob4 | ENSDARP00000156496 | ENSDARP00000072975 | Programmed cell death protein 10-A; Promotes cell proliferation. Modulates apoptotic pathways. Increases mitogen-activated protein kinase activity. Important for cell migration, and for normal structure and assembly of the Golgi complex. Important for KDR/VEGFR2 signaling. Required for normal angiogenesis, vasculogenesis and hematopoiesis during embryonic development (By similarity). Required for normal cardiovascular development. | MOB1, Mps One Binder kinase activator-like 3 (Yeast). | 0.848 |
pdcd10a | stk24b | ENSDARP00000156496 | ENSDARP00000135203 | Programmed cell death protein 10-A; Promotes cell proliferation. Modulates apoptotic pathways. Increases mitogen-activated protein kinase activity. Important for cell migration, and for normal structure and assembly of the Golgi complex. Important for KDR/VEGFR2 signaling. Required for normal angiogenesis, vasculogenesis and hematopoiesis during embryonic development (By similarity). Required for normal cardiovascular development. | Serine/threonine kinase 24b (STE20 homolog, yeast). | 0.877 |
pdcd10a | strip1 | ENSDARP00000156496 | ENSDARP00000103366 | Programmed cell death protein 10-A; Promotes cell proliferation. Modulates apoptotic pathways. Increases mitogen-activated protein kinase activity. Important for cell migration, and for normal structure and assembly of the Golgi complex. Important for KDR/VEGFR2 signaling. Required for normal angiogenesis, vasculogenesis and hematopoiesis during embryonic development (By similarity). Required for normal cardiovascular development. | Striatin-interacting protein 1 homolog; May play a role in the regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics and cell shape (By similarity). | 0.759 |
pdcd10a | strip2 | ENSDARP00000156496 | ENSDARP00000128547 | Programmed cell death protein 10-A; Promotes cell proliferation. Modulates apoptotic pathways. Increases mitogen-activated protein kinase activity. Important for cell migration, and for normal structure and assembly of the Golgi complex. Important for KDR/VEGFR2 signaling. Required for normal angiogenesis, vasculogenesis and hematopoiesis during embryonic development (By similarity). Required for normal cardiovascular development. | Striatin-interacting protein 2. | 0.759 |