STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLD5Si:ch211-194e18.2; Phospholipase D family, member 5 (481 aa)    
Predicted Functional Partners:
zbtb18
Zinc finger and BTB domain-containing protein 18; Transcriptional repressor that plays a role in various developmental processes. Specifically binds the consensus DNA sequence 5'-[AC]ACATCTG[GT][AC]-3' which contains the E box core, and acts by recruiting chromatin remodeling multiprotein complexes (By similarity)
      
 0.848
cep170a
Centrosomal protein 170a
      
 0.822
rgs7
Regulator of G-protein signalling 7
   
  
 0.797
ryr2b
Ryanodine receptor 2b (cardiac)
      
 0.561
akt3
V-akt murine thymoma viral oncogene homolog 3b; RAC-gamma serine/threonine-protein kinase
      
 0.542
gde1
Glycerophosphodiester phosphodiesterase 1
      
 0.426
abhd4
Abhydrolase domain containing 4
      
 0.405
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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