STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
klf9Kruppel-like factor 9. (216 aa)    
Predicted Functional Partners:
sin3aa
SIN3 transcription regulator family member Aa.
    
 
 0.889
slco1c1
Solute carrier organic anion transporter family member.
      
 0.644
fkbp5
Peptidylprolyl isomerase.
   
 
 0.615
tsc22d3
TSC22 domain family, member 3.
   
 
 0.511
chac1
Glutathione-specific gamma-glutamylcyclotransferase 1; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides. Glutathione depletion is an important factor for apoptosis initiation and execution. Acts as a pro-apoptotic component of the unfolded protein response pathway by mediating the pro-apoptotic effects of the ATF4-ATF3-DDIT3/CHOP cascade. Negative regulator of Notch signaling pathway involved in embryonic neurogenesis: acts by inhibiting Notch cleavage by furin, maintaining Not [...]
   
  
 0.495
qpctlb
Glutaminyl-peptide cyclotransferase-like b.
      
 0.475
spsb3a
SplA/ryanodine receptor domain and SOCS box-containing 3a.
      
 0.475
spsb3b
SplA/ryanodine receptor domain and SOCS box-containing 3b.
      
 0.475
ENSDARP00000131171
Si:dkey-23n7.10.
      
 0.475
tsc22d3-3
Si:ch211-220e11.3.
    
 
 0.473
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.